Results 51 to 60 of about 12,170,032 (208)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Automatic generation control operation with electric vehicles [PDF]
, 2010 This paper presents a methodology to make EV able tocontribute to secondary frequency regulation, byparticipating in Automatic Generation Control (AGC).The aggregator entity is used in this methodology to act asintermediate between the AGC and the EV ...
J. A. Peças Lopes +3 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Machine learning surrogates for CALPHAD inputs in mean-field precipitation modelling of IN738LC
Materials & DesignThis study presents a novel application of a machine learning-based surrogate modelling approach to replace CALPHAD-based inputs in the mean-field simulation of γ′ precipitation in the nickel-based superalloy IN738LC.
Z.Y. Cao +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
A Formulation of nonlinear model predictive control using automatic differentiation [PDF]
, 2005 An efficient algorithm is developed to alleviate the computational burden associated with nonlinear model predictive control (NMPC). The new algorithm extends an existing algorithm for solutions of dynamic sensitivity from autonomous to non-autonomous ...
Cao, Yi
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Automatic generation control: A decentralized robust approach [PDF]
, 2007 Automatic Generation Control (AGC) problem has been one of the major subjects in electric power system design/operation and is becoming much more significant today in accordance with increasing size, changing structure and complexity of interconnected ...
Mitani, Yasunori +3 more
core
Automatic Generation Control Problem in Interconnected Power Systems [PDF]
, 2013 The present article is aimed to discuss the various operational and control aspects of interconnected power systems. The structure of present day power systems is discussed and it is followed by the identification of automatic generation control (AGC ...
Hasan, Naimul +3 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source