Results 61 to 70 of about 12,871,614 (301)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Machine learning surrogates for CALPHAD inputs in mean-field precipitation modelling of IN738LC

Materials & Design
This study presents a novel application of a machine learning-based surrogate modelling approach to replace CALPHAD-based inputs in the mean-field simulation of γ′ precipitation in the nickel-based superalloy IN738LC.
Z.Y. Cao, M.J. Anderson, A. Rowe, G. Panoutsos, H.C. Basoalto   +4 more
doaj   +1 more source

Automatic Generation Control Problem in Interconnected Power Systems [PDF]

, 2013
The present article is aimed to discuss the various operational and control aspects of interconnected power systems. The structure of present day power systems is discussed and it is followed by the identification of automatic generation control (AGC ...
Hasan, Naimul, Khatoon, Shahida, Nizamuddin, Ibraheem,, Singh, Yadav   +3 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Online automatic tuning and control for fed-batch cultivation [PDF]

, 2007
Performance of controllers applied in biotechnological production is often below expectation. Online automatic tuning has the capability to improve control performance by adjusting control parameters.
Straten, G., van, Leo A. van der Pol, Anton J. B. van Boxtel, Boxtel, A.J.B., van, Pol, L.A., van der, Zita I. T. A. Soons, Soons, Z.I.T.A., Gerrit van Straten   +7 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Steady-State Interval Detection and Nonlinear Modeling for Automatic Generation Control Systems

IEEE Access, 2019
Automatic generation control systems are designed to adjust electric power outputs of multiple generators simultaneously in accordance with the current load.
Pengfei Cao, Jiandong Wang, Chao Zhang
doaj   +1 more source

Control Generation by Program Transformation [PDF]

, 2006
The objective of control generation in logic programming is to derive a computation rule for a program that is efficient and yet does not compromise program correctness. Progress in solving this fundamental problem in logic programming has been slow and,
Jonathan, Martin, King, Andy
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source