Results 101 to 110 of about 2,289,473 (322)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Automatic Vehicle Identification System Using License Plate [PDF]

open access: yes, 2011
This paper presents a new approach for development of an Automatic Vehicle Identification System (A VIS). The proposed system can be divided into three major modules; they are vehicle image preprocessing, license plate feature extraction and ...
Adetiba, E.   +5 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Formal Approach to Exploiting Multi-Stage Attacks based on File-System Vulnerabilities of Web Applications (Extended Version)

open access: yes, 2017
Web applications require access to the file-system for many different tasks. When analyzing the security of a web application, secu- rity analysts should thus consider the impact that file-system operations have on the security of the whole application ...
A Armando   +4 more
core   +1 more source

A surveillance system of a military harbour using an automatic identification system

open access: yesProceedings of the 14th International Conference on Computer Systems and Technologies, 2013
The goal of our research is the design and implementation of a surveillance system based on an Automatic Identification System (AIS). The AIS system enables operators in a control room to monitor ship movements in and along the harbour. There is a need to support human operators. The automated system is modelled after human operator.
Rothkrantz, L.J.M. (author)   +1 more
openaire   +3 more sources

Integration of Automatic Identification System (AIS) Data and Single-Channel Synthetic Aperture Radar (SAR) Images by SAR-Based Ship Velocity Estimation for Maritime Situational Awareness

open access: yesRemote Sensing, 2019
The synergic utilization of data from different sources, either ground-based or spaceborne, can lead to effective monitoring of maritime activities. To this end, the integration of synthetic aperture radar (SAR) images with data reported by the automatic
M. Graziano, A. Renga, A. Moccia
semanticscholar   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Проектирование и внедрение системы автоматической классификации документов для конечного множества языков [PDF]

open access: yes, 2009
The paper investigates the practical aspects of creating an automated system for automatic language recognition and classification of documents.
Зайцев, В. Г.   +1 more
core  

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