Results 111 to 120 of about 2,289,473 (322)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Analysis and Design of Android APP Security Reinforcement System [PDF]

open access: yesJisuanji gongcheng, 2018
In order to improve the security of Android application software and increase the difficulty of the attacker without affecting the running efficiency of APP as the target,an APP security reinforcement system is designed on the basis of the automatic ...
ZHAO Yuehua,LIU Jia
doaj  

Aspects of automation of selective cleaning [PDF]

open access: yes, 2005
Cleaning (pre-commercial thinning) is a silvicultural operation, primarily used to improve growing conditions of remaining trees in young stands (ca. 3 - 5 m of height). Cleaning costs are considered high in Sweden and the work is laborious.
Vestlund, Karin
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

VLCC’s fuel consumption prediction modeling based on noon report and automatic identification system

open access: yesCogent Engineering, 2019
It is extremely important for fuel saving by taking the correct decisions where cost efficiency and environmental friendliness are top priorities. The fuel consumption rate of the ship is influenced by many parameters, such as average daily sailing speed,
Ali Akbar Safaei   +2 more
doaj   +1 more source

Evaluation of Anonymized ONS Queries [PDF]

open access: yes, 2008
Electronic Product Code (EPC) is the basis of a pervasive infrastructure for the automatic identification of objects on supply chain applications (e.g., pharmaceutical or military applications).
Barbeau, Michel   +2 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Past, present, and future of the satellite-based automatic identification system: areas of applications (2004–2016)

open access: yesWMU Journal of Maritime Affairs (JoMA), 2018
In 2016, the world shipping fleet grew by 3.5%. Even if the annual growth rate remains at its lowest since 2013, the global situation is still in overcapacity (UNCTAD 2016). Ninety percent of global trade, by volume, is done by sea. Monitoring this fleet
M. Fournier   +3 more
semanticscholar   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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