Results 21 to 30 of about 26,748 (274)

Automatic feature recognition using artificial neural networks to integrate design and manufacturing: Review of automatic feature recognition systems

, 2010
Feature technology is considered an essential tool for integrating design and manufacturing. Automatic feature recognition (AFR) has provided the greatest contribution to fully automated computer-aided process planning system development.
Miljković, Zoran, Zoran Miljković, Nenad Nešić, Bojan R. Babić, Nesić, Nenad, Babić, Bojan   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Automatic (offline) configuration of algorithms

, 2013
Most optimization algorithms, including evolutionary algorithms and metaheuristics, and general-purpose solvers for integer or constraint programming, have often many parameters that need to be properly configured (i.e., tuned) for obtaining the best ...
López-Ibáñez, Manuel; id_orcid, Thomas Stützle, Manuel López-Ibáñez, Sẗutzle, Thomas   +3 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Reinforcement learning for path planning of free-floating space robotic manipulator with collision avoidance and observation noise

Frontiers in Control Engineering
This study introduces a novel approach for the path planning of a 6-degree-of-freedom free-floating space robotic manipulator, focusing on collision and obstacle avoidance through reinforcement learning.
Ahmad Al Ali, Zheng H. Zhu
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Automatic Generation of Multi-Objective Polyhedral Compiler Transformations

, 2020
To this day, polyhedral optimizing compilers use either extremelyrigid (but accurate) cost models, one-size-fits-all general-purposeheuristics, or auto-tuning strategies to traverse and evaluate largeoptimization spaces.In this paper, we introduce an ...
Tobias Grosser, Kong, Martin, Henk Corporaal, Gysi, Tobias, Lorenzo Chelini, Tobias Gysi, Martin Kong, Chelini, Lorenzo, Corporaal, Henk, Grosser, Tobias   +9 more
core   +1 more source

An approach to online identification of Takagi-Sugeno fuzzy models [PDF]

, 2004
An approach to the online learning of Takagi-Sugeno (TS) type models is proposed in the paper. It is based on a novel learning algorithm that recursively updates TS model structure and parameters by combining supervised and unsupervised learning.
Angelov, Plamen, Filev, Dimitar, P.P. Angelov, D.P. Filev   +3 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Term conflation methods in information retrieval: non-linguistic and linguistic approaches [PDF]

, 2005
Purpose – To propose a categorization of the different conflation procedures at the two basic approaches, non-linguistic and linguistic techniques, and to justify the application of normalization methods within the framework of linguistic techniques ...
Galvez, Carmen, Felix de Moya-Anegon, Felix, Herrero-Solana, Victor   +2 more
core