Results 41 to 50 of about 26,907 (274)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
An approach to online identification of Takagi-Sugeno fuzzy models [PDF]
, 2004 An approach to the online learning of Takagi-Sugeno (TS) type models is proposed in the paper. It is based on a novel learning algorithm that recursively updates TS model structure and parameters by combining supervised and unsupervised learning.
Angelov, Plamen +3 more
core +1 more source
Nuevas Estrategias de Control Glucémico en Pacientes con Diabetes Mellitus Tipo 1
Revista Iberoamericana de Automática e Informática Industrial RIAI, 2019 Actualmente la diabetes mellitus es un problema de salud pública mundial. En este trabajo, se proponen estrategias de control para mantener los niveles de glucosa en sangre de pacientes diabéticos tipo 1 en los rangos ideales en pro de la salud del ...
Pablo S. Rivadeneira +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Term conflation methods in information retrieval: non-linguistic and linguistic approaches [PDF]
, 2005 Purpose – To propose a categorization of the different conflation procedures at the two basic approaches, non-linguistic and linguistic techniques, and to justify the application of normalization methods within the framework of linguistic techniques ...
Galvez, Carmen +2 more
core
Revista Iberoamericana de Automática e Informática Industrial RIAI, 2015 No ...
Joseba Quevedo
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
On measuring the impact of hyperlinks on reading [PDF]
, 2013 We increasingly spend a vast amount of time on the Web and much of that time is spent reading. One of the main differences between reading non-Web based text and reading on the Web is the presence of hyperlinks within the text, linking various related ...
Fitzsimmons, Gemma +5 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
A novel topic model for automatic term extraction [PDF]
, 2013 Automatic term extraction (ATE) aims at extracting domain-specific terms from a corpus of a certain domain. Termhood is one essential measure for judging whether a phrase is a term.
Tao Song +14 more
core +1 more source