Results 81 to 90 of about 70,289 (311)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Integration of Low-Cost GNSS and Monocular Cameras for Simultaneous Localization and Mapping
Sensors, 2018 Low-cost Global Navigation Satellite System (GNSS) receivers and monocular cameras are widely used in daily activities. The complementary nature of these two devices is ideal for outdoor navigation.
Xiao Chen +4 more
doaj +1 more source
Hybrid Sequence Networks for Unsupervised Water Properties Estimation From Hyperspectral Imagery
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021 Generating accurate estimation of water inherent optical properties (IOPs) from hyperspectral images plays a significant role in marine exploration. Traditional methods mainly adopt bathymetric models and numerical optimization algorithms to deal with ...
Jiahao Qi +5 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Millimeter-wave ATR: a study on feature robustness
, 2022 S.247-255Three target types, namely T72, ZSU 23-4 and BMP-2 were measured in a tower/turntable configuration in several articulations each. A set of geometric, statistical, structural and polarimetric features is used to study the robustness of ...
Schimpf, H.
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 2019 Radars, as active detection sensors, are known to play an important role in various intelligent devices. Target recognition based on high-resolution range profile (HRRP) is an important approach for radars to monitor interesting targets.
Hussain, Amir +11 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Hot spot detection and classification in LWIR videos for person recognition
, 2013 Paper 87440FPerson recognition is a key issue in visual surveillance. It is needed in many security applications such as intruder detection in military camps but also for gaining situational awareness in a variety of different safety applications.
Michael Teutsch +3 more
core +1 more source