Results 111 to 120 of about 650,481 (302)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Intelligent Automation and Computer Engineering
, 2020 Intelligent Automation and Computer Engineering offers the state of the art oftremendous advances in intelligent automation and computer engineering and also ..
Cruickshank, Haitham +2 more
core +1 more source
AutomationAdvancements in robotics and computer vision are transforming how infrastructure is monitored and maintained. This paper presents a novel, fully automated pipeline for pavement condition assessment that integrates real-time image analysis with PCI ...
Nada El Desouky +4 more
doaj +1 more source
Ethical Foreground and Background in Adult Educator Work
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley +1 more source
Automation of Configuration Management of TIM Mobile Core Network Functions
, 2022 reservedThe objective of this thesis is to design and implement automation solutions for the analysis and modification of the configuration of the Core Network Functions in TIM's Configuration Management systems.
GALIZIO, DANIELE
core
Evaluation of Pavement Marking Damage Degree Based on Rotating Target Detection in Real Scenarios
AutomationDamaged road markings are widespread, and timely detection and repair of severely damaged areas is critical to the maintenance of transport infrastructure.
Zheng Wang +3 more
doaj +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
AutomationCurrent functional safety mechanisms mainly control the access points and perimeters of manufacturing cells without guaranteeing the integrity of their internal components or the absence of unauthorized humans or objects. In this work, we present a novel
Jesús Fernández-Iglesias +2 more
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source