Results 91 to 100 of about 494,406 (315)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Automotive automation: Investigating the impact on drivers' mental workload

open access: yes, 1997
Recent advances in technology have meant that an increasing number of vehicle driving tasks are becoming automated. Such automation poses new problems for the ergonomist.
Young, Mark S.   +3 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Plant Automation Acceleratorin käyttö automaatiosuunnittelussa [PDF]

open access: yes, 2019
Opinnäytetyön tarkoituksena oli tehdä Insta Automation Oy:lle käyttöohje Plant Automation Acceleratorin käyttöön, joka on Siemensin kehittämä ohjelma PCS 7-prosessinohjausjärjestelmän tueksi.
Aikio, Jere
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Automated Robotic Process Automation: A Self-Learning Approach

open access: yes, 2019
Robotic Process Automation (RPA) recently gained a lot of attention, in both industry and academia. RPA embodies a collection of tools and techniques that allow business owners to automate repetitive manual tasks. The intrinsic value of RPA is beyond dispute, e.g., automation reduces errors and costs and thus allows us to increase the overall business ...
Junxiong Gao   +3 more
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Automation of Configuration Management of TIM Mobile Core Network Functions

open access: yes, 2022
reservedThe objective of this thesis is to design and implement automation solutions for the analysis and modification of the configuration of the Core Network Functions in TIM's Configuration Management systems.
GALIZIO, DANIELE
core  

From Automated Verification to Automated Design

open access: yesProceedings of the International Conference on Automated Planning and Scheduling, 2010
In this talk I will review 50 years of research on the design-synthesis problem and show how the automata-theoretic approach can be used to solve it.
openaire   +2 more sources

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