Results 91 to 100 of about 1,562,274 (349)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Automatic Irrigation System Based on Computer Vision and an Artificial Intelligence Technique Using Raspberry Pi

Automation
Efficient irrigation water use directly affects crop productivity as demand increases for various agricultural products due to population growth worldwide.
Munir Oudah, Ali Al-Naji, Thooalnoon Y. AL-Janabi, Dhuha S. Namaa, Javaan Chahl   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

User expectations of partial driving automation capabilities and their effect on information design preferences in the vehicle [PDF]

, 2019
Partially automated vehicles present interface design challenges in ensuring the driver remains alert should the vehicle need to hand back control at short notice, but without exposing the driver to cognitive overload.
Birrell, Stewart A., Cain, Rebecca, Jennings, Paul. A., Mouzakitis, Alexandros, Skrypchuk, Lee, Thompson, Simon, Ulahannan, Arun   +6 more
core   +2 more sources

Deep Learning-Based Detection and Segmentation of Damage in Solar Panels

Automation
Renewable energy can lead to a sustainable future and solar energy is one the primary sources of renewable energy. Solar energy is harvested mainly by photovoltaic plants.
Ayesha Shaik, Ananthakrishnan Balasundaram, Lakshmi Sairam Kakarla, Nivedita Murugan   +3 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Human-automation collaboration in manufacturing: identifying key implementation factors [PDF]

, 2013
Human-automation collaboration refers to the concept of human operators and intelligent automation working together interactively within the same workspace without conventional physical separation.
Charalambous, George, Fletcher, Sarah R., Webb, Philip   +2 more
core  

Intelligent monitoring of the health and performance of distribution automation [PDF]

, 2011
With a move to 'smarter' distribution networks through an increase in distribution automation and active network management, the volume of monitoring data available to engineers also increases.
Catterson, Victoria, Davidson, Euan, Kirkwood, John, Mcarthur, Stephen, Rudd, Susan, Strachan, Scott   +5 more
core   +1 more source

Accelerated Transfer Learning for Cooperative Transportation Formation Change via SDPA-MAPPO (Scaled Dot Product Attention-Multi-Agent Proximal Policy Optimization)

Automation
A method for cooperative transportation, which required formation change in a traveling environment, is gaining interest. Deep reinforcement learning is used in formation changes for multi-robot cases.
Almira Budiyanto, Keisuke Azetsu, Nobutomo Matsunaga   +2 more
doaj   +1 more source