Results 81 to 90 of about 623,583 (292)

Mitigation of Human Supervisory Control Wait Times through Automation Strategies [PDF]

open access: yes, 2005
The application of network centric operations principles to human supervisory control (HSC) domains means that humans are increasingly being asked to manage multiple simultaneous HSC processes. However, increases in the number of available information
Mitchell, P. J.   +2 more
core  

Tunable Automation in Automated Program Verification

open access: yesCoRR
Automated verification tools based on SMT solvers have made significant progress in verifying complex software systems. However, these tools face a fundamental tension between automation and performance when dealing with quantifier instantiation -- the primary source of incompleteness and verification slowdown in SMT-based verifiers.
Alexander Y. Bai   +2 more
openaire   +3 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

From Automated Verification to Automated Design

open access: yesProceedings of the International Conference on Automated Planning and Scheduling, 2010
In this talk I will review 50 years of research on the design-synthesis problem and show how the automata-theoretic approach can be used to solve it.
openaire   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The effects of automation in libraries: the implications for work organisation and job design [PDF]

open access: yes, 1988
The purpose of this thesis was to investigate how libraries, as organisations, may adapt to the introduction of automation, specifically the use of computing technology. The study focusses on the effects on the organisation of work. The thesis commences
Graham, Margaret Elizabeth
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Automated journalism

open access: yes
Developed as a response to the increasing popularity of data-driven journalism, automated journalism refers to the process of automating the collection, production, and distribution of news content and other data with the assistance of computer programs.
Wang Ngai Yeung, Tomás Dodds
openaire   +2 more sources

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