Results 81 to 90 of about 1,562,274 (349)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Disassembly Plan Representation by Hypergraph

open access: yesAutomation
To be successful in a circular economy, it is important to keep the cost of operationalizing remanufacturing processes low in order to retain as much value of the product as possible.
Abboy Verkuilen   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Effects of automation on situation awareness in controlling robot teams [PDF]

open access: yes, 2010
Declines in situation awareness (SA) often accompany automation. Some of these effects have been characterized as out-of-the-loop, complacency, and automation bias.
Lewis, Michael, Sycara, Katia
core   +1 more source

Advanced Data Classification Framework for Enhancing Cyber Security in Autonomous Vehicles

open access: yesAutomation
Autonomous vehicles (AVs) have revolutionized the automotive industry by leveraging data to perceive and interact with their environment effectively.
Shiva Ram Neupane, Weiqing Sun
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A comprehensive review on automation in agriculture using artificial intelligence

open access: yesArtificial Intelligence in Agriculture, 2019
Agriculture automation is the main concern and emerging subject for every country. The world population is increasing at a very fast rate and with increase in population the need for food increases briskly.
Kirtan Jha   +3 more
semanticscholar   +1 more source

Robotic Process Automation and Artificial Intelligence in Industry 4.0 - A Literature review

open access: yesCENTERIS/ProjMAN/HCist, 2020
Taking into account the technological evolution of the last decades and the proliferation of information systems in society, today we see the vast majority of services provided by companies and institutions as digital services. Industry 4.0 is the fourth
Jorge Ribeiro   +3 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Automotive automation: Investigating the impact on drivers' mental workload [PDF]

open access: yes, 1997
Recent advances in technology have meant that an increasing number of vehicle driving tasks are becoming automated. Such automation poses new problems for the ergonomist.
Stanton, N A, Young, M S
core  

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