Results 61 to 70 of about 494,406 (315)
The effects of automation in libraries: the implications for work organisation and job design [PDF]
, 1988 The purpose of this thesis was to investigate how libraries, as organisations, may adapt to the introduction of automation, specifically the use of computing technology. The study focusses on the effects on the organisation of work. The thesis commences
Graham, Margaret Elizabeth
core
Proceedings of the 5th international symposium on Non-photorealistic animation and rendering, 2007 Pictures taken from different view points cannot be stitched into a geometrically consistent mosaic, unless the structure of the scene is very special. However, geometrical consistency is not the only criterion for success: incorporating multiple view points into the same picture may produce compelling and informative representations. A multi viewpoint
Zelnik-Manor, Lihi, Perona, Pietro
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Advanced Data Classification Framework for Enhancing Cyber Security in Autonomous Vehicles
AutomationAutonomous vehicles (AVs) have revolutionized the automotive industry by leveraging data to perceive and interact with their environment effectively.
Shiva Ram Neupane, Weiqing Sun
doaj +1 more source
Journal of Symbolic Computation, 1985 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Lattice-Automation/seqfold: 0.7.17
, 2023 Full Changelog: https://github.com/Lattice-Automation/seqfold/compare/0.7.7...0.7.17 fix dot_bracket output length: https://github.com/Lattice-Automation/seqfold/issues ...
Kevin, Joshua Timmons
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source