Results 41 to 50 of about 944,848 (299)

Development of a weighted scoring system for the Electronic Driving Observation Schedule (eDOS)

open access: yesMethodsX, 2020
The electronic Driving Observation Schedule (eDOS) is a novel approach to assessing older drivers’ performance in their everyday driving environment on their chosen routes.
Yu-Ting Chen   +2 more
doaj   +1 more source

International Regulations for Automobile Driving and Epilepsy [PDF]

open access: yesJournal of Travel Medicine, 2006
Many patients with epilepsy travel abroad and drive automobiles with the assumption that policies, rules, and regulations on epilepsy and driving are similar to those of their home countries. This paper investigates the driving restrictions and other pertinent information on this issue in foreign countries.A questionnaire was sent to 231 neurologists ...
W W, Ooi, J A, Gutrecht
openaire   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A Review on Fatigue Driving Detection

open access: yesITM Web of Conferences, 2017
The socialization of automobile development has brought great convenience to people’s travel. However, the rapid increase in the number of vehicles has also caused a series of problems.
Shi Sheng-Yang   +2 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Driving against the Power: Sexism in Automobile Culture and Female Drivers in Turkey

open access: yesJournal of Economy Culture and Society, 2022
This article’s aim is to understand the socio-historical factors behind sexist judgments against female drivers in Turkey, based on written and visual media, social media content with the theme of “female driver errors,” and everyday male conversations ...
Sefer Yetkin Işık   +1 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Safe driving in a green world : a review of driver performance benchmarks and technologies to support ‘smart’ driving [PDF]

open access: yes, 2011
Road transport is a significant source of both safety and environmental concerns. With climate change and fuel prices increasingly prominent on social and political agendas, many drivers are turning their thoughts to fuel efficient or ‘green’ (i.e ...
Mark S. Young   +5 more
core   +1 more source

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