Results 271 to 280 of about 85,000 (343)

Investigation of the Structural, Mechanical and Operational Properties of an Alloy AlSi18Cu3CrMn. [PDF]

Materials (Basel)
Dimova D, Dochev B, Trojan K, Kamarska K, Sofronov Y, Zagorski M, Tsonev V, Nikolov A.   +7 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Solar radiation impact on nanofluid flow and heat transfer between magnetized stretchable discs with variable thermal properties. [PDF]

Sci Rep
Zahir H, Hussain M, Ahmad H, Faridi AA, Khan N, Abulhassan MEE, Guedri K, Almaliki AH.   +7 more
europepmc   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source

Machine learning and experimental emission assessment in high temperature air premixed charged compression ignition engines using the Pugh matrix. [PDF]

Sci Rep
Al Awadh M, Goh KOM.
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

A Comprehensive Review of Artificial Intelligence-Based Algorithms for Predicting the Remaining Useful Life of Equipment. [PDF]

Sensors (Basel)
Li W, Chen J, Chen S, Li P, Zhang B, Wang M, Yang M, Wang J, Zhou D, Yun J.   +9 more
europepmc   +1 more source

An Ultrathin, Cyano‐Functionalized Copolymeric Memristor by iCVD Process for Driving Convolutional Neural Networks of High‐Resolution Images

Advanced Science, EarlyView.
Two‐terminal polymer memristors based on cyano‐functionalized copolymer films are developed via a solvent‐free, initiated chemical vapor deposition (iCVD) process for high‐resolution image classification. Molecularly engineered p(CEA‐co‐DEGDVE) films enable stable, linear, and symmetric conductance modulation, supporting multi‐level weight mapping in ...
Ji In Kim, Minsu So, Woo Jin Wang, Taehoon Kim, Eun Su Jeong, Kyumin Sim, Hamin Park, Sung Kyu Kim, Yong Goo Shin, Junhwan Choi, Min Ju Kim   +10 more
wiley   +1 more source

Audio-Based Engine Fault Diagnosis with Wavelet, Markov Blanket, ROCKET, and Optimized Machine Learning Classifiers. [PDF]

Sensors (Basel)
Tuleski BL, Yamaguchi CK, Stefenon SF, Coelho LDS, Mariani VC.   +4 more
europepmc   +1 more source