Results 21 to 30 of about 358,824 (288)

Traffic Flow Model for Coordinated Traffic Light Systems

open access: yesEngineering Proceedings
Traffic in large cities is increasing due to continuous urbanization, the construction of new housing complexes and the accompanying new street network. The growth of cities creates prerequisites for increasing the intensity of transport, pedestrian, and
Iliyan Andreev   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Business records of Standard Automobile Company of Wichita, Kansas

open access: yes, 1909
This folder contains business records of Standard Automobile Company of Wichita, Kansas, dated between November 23, 1909 and November 21, 1910. There are receipts for parts, requests for autos, and a letter to Mr. Rising asking about conditions in Buenos
Standard Automobile Company of Wichita, Kansas
core   +5 more sources

Research and Analysis of Traffic Intensity on a Street with High Traffic Load: Case Study of the City of Sofia

open access: yesEngineering Proceedings
The study of traffic parameters in cities is the basis for making adequate decisions related to the organization and regulation of traffic. This publication presents a study of one of the main parameters of transport flows, namely, its intensity.
Durhan Saliev   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Concept as a stage of designing and evaluating car consumer properties

open access: yesВестник университета
The role of concept cars in designing and evaluating car consumer properties, such as interior and exterior design, functional features, and positioning, has been considered.
D. F. Karimov
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Parameters Characterizing the Performance of Automotive Electronic Control Systems on Petrol Engine Emissions

open access: yesEngineering Proceedings
It is evident that a novel engineering solution is required in order to elevate a greater number of polluting cars into a higher category. There appears to be a paucity of direct interest in upgrading Euro 1, 2, 3, 4, and 5 vehicles to the highest ...
Hristo Konakchiev, Evgeni Dimitrov
doaj   +1 more source

Investigation on the effect of the flow passage geometry of diesel injector nozzle on injection process parameters and engine performances

open access: yesEnergy Science & Engineering, 2022
In the paper, the method based on optimization of flow passage geometry of diesel injector nozzle to improve the quality of fuel injection and atomization process has been studied. Designs of injector nozzles have been developed to enhance the quality of
Vladimir Markov   +4 more
doaj   +1 more source

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