Results 31 to 40 of about 2,511 (265)

Concept as a stage of designing and evaluating car consumer properties

open access: yesВестник университета
The role of concept cars in designing and evaluating car consumer properties, such as interior and exterior design, functional features, and positioning, has been considered.
D. F. Karimov
doaj   +1 more source

Investigation on the effect of the flow passage geometry of diesel injector nozzle on injection process parameters and engine performances

open access: yesEnergy Science & Engineering, 2022
In the paper, the method based on optimization of flow passage geometry of diesel injector nozzle to improve the quality of fuel injection and atomization process has been studied. Designs of injector nozzles have been developed to enhance the quality of
Vladimir Markov   +4 more
doaj   +1 more source

Effect of fullerene-like nanoparticles at low concentrations on the anti-wear properties of motor fuels

open access: yesПроблеми трибології, 2022
Motor fuels are the source of energy for internal combustion engines, and also a lubricant for friction units of the fuel equipment of automobile, aircraft and ship engines.
V.S. Pyliavsky   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Parameters Characterizing the Performance of Automotive Electronic Control Systems on Petrol Engine Emissions

open access: yesEngineering Proceedings
It is evident that a novel engineering solution is required in order to elevate a greater number of polluting cars into a higher category. There appears to be a paucity of direct interest in upgrading Euro 1, 2, 3, 4, and 5 vehicles to the highest ...
Hristo Konakchiev, Evgeni Dimitrov
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Influence of Engine Load on Soot Mass Concentration and Morphology in Diesel Exhaust

open access: yesAtmosphere
This study investigates the relationship between exhaust gas composition, particle number (PN) emissions, and soot microstructure of a 1.9 L compression-ignition engine operated under six controlled steady-state load regimes at 2000 min−1.
Iliyan Damyanov   +3 more
doaj   +1 more source

Estimation of Engine Intake Air Mass Flow using a generic Speed-Density method

open access: yesJournal of Middle European Construction and Design of Cars, 2014
Measurement of real driving emissions (RDE) from internal combustion engines under real-world operation using portable, onboard monitoring systems (PEMS) is becoming an increasingly important tool aiding the assessment of the effects of new fuels and ...
Vojtíšek Michal, Kotek Martin
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

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