ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Coordinating innovation without unified authority: leadership and organizational identification in hybrid organizations. [PDF]
Fu Y, Zhong YH, Agudamu, Zhang WL.
europepmc +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Graphene battery as a viable alternative in electric vehicles for enhanced charging efficiency and thermal management. [PDF]
Srikrishna N, Shetty DD, Kini CR.
europepmc +1 more source
‘Where are the adults?’: Troubling child‐activism and children's political participation
Abstract Children's political participation is a well‐established theme in childhood studies. In this article we offer an original account of child activism that takes into account the entangled and emergent aspect of children as activists. We begin with a historical and a conceptual review, noting the importance of mid‐20th century developments such ...
Sharon Hunter, Claire Cassidy
wiley +1 more source
University students' awareness of the social dimension of sustainable transportation: The case of Amasya/Turkey. [PDF]
Şendoğdu S, Nergiz C.
europepmc +1 more source
Addressing racialised awarding gap in higher education: Insights from personal tutors
Abstract Situated within a wider cross‐institutional research project, this article provides an in‐depth case study of one higher education (HE) institution, focusing on how personal tutors make sense of racialised degree awarding disparities for both undergraduate and postgraduate students, how they perceive their responsibilities, the challenges and ...
Benjamin Ajibade +3 more
wiley +1 more source
The characteristics of chronic benzene poisoning in 176 Chinese occupational population cases. [PDF]
Gou L +7 more
europepmc +1 more source
Since late 2021, serious allegations have been made against physicist Erwin Schrödinger, ranging from pedophilia to serial sexual abuse. These accusations have significantly tarnished the Nobel Prize winner's public reputation. The ongoing debate has repeatedly raised the question of whether, and to what extent, these grave allegations are justified ...
Magdalena Gronau, Martin Gronau
wiley +1 more source
From drivers to passengers: concept of passive drink driving and need for passenger-centric interventions to reduce drink-driving in Bengaluru City, India. [PDF]
Sukumar GM +11 more
europepmc +1 more source

