Results 1 to 10 of about 125,232 (287)

A Reversible Low Frequency Alternating Current Nerve Conduction Block Applied to Mammalian Autonomic Nerves [PDF]

Sensors, 2021
Electrical stimulation can be used to modulate activity within the nervous system in one of two modes: (1) Activation, where activity is added to the neural signalling pathways, or (2) Block, where activity in the nerve is reduced or eliminated.
M. Ivette Muzquiz, Landan Mintch, M. Ryne Horn, Awadh Alhawwash, Rizwan Bashirullah, Michael Carr, John H. Schild, Ken Yoshida   +7 more
doaj   +5 more sources

Spatiotemporal parameters for energy efficient kilohertz-frequency nerve block with low onset response

Journal of NeuroEngineering and Rehabilitation, 2023
Background Electrical nerve conduction block has great potential for treatment of disease through reversible and local inactivation of somatic and autonomic nerves. However, the relatively high energy requirements and the presence of undesired excitation
Edgar Peña, Nicole A. Pelot, Warren M. Grill   +2 more
doaj   +2 more sources

Kilohertz waveforms optimized to produce closed-state Na+ channel inactivation eliminate onset response in nerve conduction block.

PLoS Computational Biology, 2020
The delivery of kilohertz frequency alternating current (KHFAC) generates rapid, controlled, and reversible conduction block in motor, sensory, and autonomic nerves, but causes transient activation of action potentials at the onset of the blocking ...
Guosheng Yi, Warren M Grill
doaj   +2 more sources

Stimulation parameters for directional vagus nerve stimulation

Bioelectronic Medicine, 2023
Background Autonomic nerve stimulation is used as a treatment for a growing number of diseases. We have previously demonstrated that application of efferent vagus nerve stimulation (eVNS) has promising glucose lowering effects in a rat model of type 2 ...
Joel Villalobos, Sophie C. Payne, Glenn M. Ward, Sofianos Andrikopoulos, Tomoko Hyakumura, Richard J. MacIsaac, James B. Fallon   +6 more
doaj   +2 more sources

Sympathetic nerve blocks for posttraumatic stress disorder: an evidentiary review for future clinical trials

Frontiers in Psychiatry, 2023
Posttraumatic stress disorder (PTSD) is a chronic disorder resulting from exposure to traumatic events. In recent years, sympathetic nerve blocks have gained interest as an emerging treatment modality for PTSD.
Sakshi Prasad, Nityanand Jain, Tungki Pratama Umar, Igor Radenkov, Sirwan Khalid Ahmed, Virginia Sakagianni, Sofia Kollia, Mohmed Junaid Hingora, Nikita Kumari, Amir Reza Akbari, Lubova Renemane, Anil Bachu   +11 more
doaj   +2 more sources

Post-stroke hemiplegic limb cold sensation and sympathetic nervous regulation: A review [PDF]

Journal of International Medical Research
Purpose This review aimed to compare the efficacy of various sympathetic nerve regulation techniques in the treatment of cold sensations or abnormal sweating in hemiplegic limbs following stroke, providing guidance for managing autonomic nervous system ...
Mingqing Yu, Ping Xu, Hanrui Fan, Yong Fei   +3 more
doaj   +2 more sources

Anodal block permits directional vagus nerve stimulation

Scientific Reports, 2020
Vagus nerve stimulation (VNS) is a bioelectronic therapy for disorders of the brain and peripheral organs, and a tool to study the physiology of autonomic circuits.
Umair Ahmed, Yao-Chuan Chang, Marina Cracchiolo, Maria F. Lopez, Jacquelyn N. Tomaio, Timir Datta-Chaudhuri, Theodoros P. Zanos, Loren Rieth, Yousef Al-Abed, Stavros Zanos   +9 more
doaj   +2 more sources

Anatomy, Imaging, and Clinical Significance of the Cervicothoracic (Stellate) Ganglion [PDF]

Diagnostics
Background/Objectives: The stellate ganglion (SG), formed by the fusion of the inferior cervical and first thoracic sympathetic ganglia in approximately 80% of individuals, plays crucial roles in cardiac innervation, pain management, and autonomic ...
Mugurel Constantin Rusu, Ionuţ Mădălin Munteanu, Alexandra Diana Vrapciu, Adelina Maria Jianu, Sorin Hostiuc, Răzvan Costin Tudose, Andrei Gheorghe Marius Motoc   +6 more
doaj   +2 more sources

Blocking Aδ- and C-fiber neural transmission by sub-kilohertz peripheral nerve stimulation

Frontiers in Neuroscience
IntroductionWe recently showed that sub-kilohertz electrical stimulation of the afferent somata in the dorsal root ganglia (DRG) reversibly blocks afferent transmission.
Shaopeng Zhang, Longtu Chen, Sajjad Rigi Ladez, Ahmet Seferge, Jia Liu, Bin Feng   +5 more
doaj   +2 more sources

Efficacy of the lumbar sympathetic ganglion block in lower limb pain and its application prospects during the perioperative period

Ibrain, 2022
The sympathetic nervous system is involved in the physiological pathogenesis of many different types of chronic pain. Sympathetic blocks can interrupt the reflex control system by intercepting the noxious afferent fibers accompanying autonomic nerves ...
Jing‐Han Zhang, Yan‐Ping Deng, Min‐Jian Geng   +2 more
doaj   +2 more sources