Advanced Science, EarlyView.A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong +17 more
wiley +1 more source
Adjunctive ultrasound-guided vagus nerve-targeted pharmacopuncture for refractory fibromyalgia with autonomic symptoms: a case report. [PDF]
Front Med (Lausanne)Lee JH, Lee YU, Choi TH, Lee S, Lee S.
europepmc +1 more source
Perceived Time Shapes Physical Fatigue Accumulation and Its Neural Oscillatory Correlates
Advanced Science, EarlyView.Can a clock change the course of physical fatigue? By covertly manipulating the clock calibration during repeated isometric contractions, we showed that perceived time shapes fatigue accumulation and frontal oscillatory dynamics. While fatigue accumulation was only reduced when the clock was slowed down, frontal oscillatory dynamics followed perceived ...
Pierre‐Marie Matta +3 more
wiley +1 more source
Pan-Neurofascin Antibody-Associated Nodopathy: A Critical Guillain-Barré Syndrome Mimic in the Differential Diagnosis-Report of Two Cases. [PDF]
Case Rep Crit CareNemethova A +3 more
europepmc +1 more source
Advanced Science, EarlyView.An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang +3 more
wiley +1 more source
Clinical Outcomes of Ultrasound-Guided Stellate Ganglion Block in Highly Treatment-Resistant Chronic Migraine: A 6-Month Prospective Single-Group Interventional Study. [PDF]
Medicina (Kaunas)Dadali S +5 more
europepmc +1 more source
Advanced Science, EarlyView.As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia +13 more
wiley +1 more source
Short-Lasting Unilateral Neuralgiform Headache Attacks With Conjunctival Injection and Tearing (SUNCT) Across Two Decades: Longitudinal Characterization and Multimodal Management of a Refractory Case. [PDF]
CureusSilva GP +3 more
europepmc +1 more source
Advanced Science, EarlyView.This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
Cardioneuroablation for Reflex Syncope and Functional Bradyarrhythmias: A State-of-the-Art Review. [PDF]
J Clin MedSan Antonio R +10 more
europepmc +1 more source