Results 141 to 150 of about 20,075,313 (301)

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Attenuated maximum heart rate following ultra endurance cycling and the role of the autonomic nervous system: An exploratory study.

open access: yes
Ultra-endurance exercise challenges cardiovascular and autonomic regulation. Few studies track heart rate (HR), ventilatory, and autonomic markers across pre-race, immediately post-race, and recovery phases in the same athletes.
Gaze, D.C.   +3 more
core  

Essential Updates 2024–2026: Advances in Colorectal Cancer Surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Surgical innovation in colorectal cancer is increasingly judged not by technical feasibility alone, but by whether it improves oncological outcomes, preserves function, reduces morbidity, or makes difficult procedures more reproducible. This structured narrative review examines major surgical studies published from January 2024 through July ...
Hiroyasu Kagawa, Yusuke Kinugasa
wiley   +1 more source

Nephrotic proteinuria and the autonomic nervous system

open access: yes, 2007
The complex neroendocrine mechanism of nephrotic protenuria is focused on the role played by the autonomic nervous ...
CAMICI, MARCELLO
core  

Short‐Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer: A Multicenter Propensity Score‐Matched Analysis Comparing Patients With and Without Preoperative Neoadjuvant Therapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To evaluate the association between preoperative neoadjuvant therapy and short‐term outcomes of transanal total mesorectal excision for rectal cancer. Methods We retrospectively analyzed patients who underwent transanal total mesorectal excision at 26 Japanese institutions between 2012 and 2019.
Takafumi Shima   +57 more
wiley   +1 more source

The enteric nervous system in physiological and pathological conditions

open access: yes
The enteric nervous system is a specific part of the autonomic nervous system, whose role is mainly concerned with ensuring the proper functioning of the gastrointestinal tract.
Tadeusz Kuder   +2 more
core   +1 more source

Local Recurrence and Oncological Outcomes After Transanal Total Mesorectal Excision With Intersphincteric Resection for Lower Rectal Cancer: A Nationwide Multicenter Cohort Study (Ta‐Ta‐Mi Study)

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The 3‐year local recurrence (LR), recurrence‐free survival, and overall survival rates were 7.3%, 79.5%, and 98.1%, respectively. Multivariable analysis identified circumferential resection margin (CRM)/radial margin (RM) positivity as an independent risk factor for LR.
Kan Tanabe   +12 more
wiley   +1 more source

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