Results 201 to 210 of about 146,347 (350)

The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Effect of Add‐on Aliskiren to Type 1 Angiotensin Receptor Blocker Therapy on Endothelial Function and Autonomic Nervous System in Hypertensive Patients With Ischemic Heart Disease

, 2014
Atsuko Ozeki, Eisuke Amiya, Masafumi Watanabe, Yumiko Hosoya, Munenori Takata, Aya Watanabe, Shuichi Kawarasaki, Tomoko Nakao, Shogo Watanabe, Kazuko Omori, Namie Yamada, Yukiko Tahara, Yasunobu Hirata, Ryozo Nagai   +13 more
openalex   +2 more sources

Parkinson’s disease and metabolic disorders, understanding their shared co-morbidity through the autonomic nervous system [PDF]

Thanh Pham, Rebecca E Schelling, Ken H. Loh   +2 more
openalex   +1 more source

Assessing Autonomic Nervous System Function by Pulse Rate Variability in Patients with Chronic Obstructive Pulmonary Disease

, 2023
Yuki Hirayama, Miyako Takata, Akira Yamasaki, Masahiko Katô, Naoto Burioka   +4 more
openalex   +2 more sources

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai, Shriarjun Shastry, Morgan R. Hurst, Arianna Minzoni, Eduardo Barbieri, Luke Remmler, Eugene N. Muratov, Michael A. Daniele, Stefano Menegatti, Alexander Tropsha   +9 more
wiley   +1 more source

Functional Visual Symptoms, Accommodative Dysfunction, and Visual Performance Alterations in Chronic Work-Related Stress: A Narrative Review. [PDF]

Vision (Basel)
Malvasi M, Pacella E, De Sio S, Covelli GP.   +3 more
europepmc   +1 more source

Autonomic nervous system modulation affects the inflammatory immune response in mice with acute Chagas disease

, 2012
Marcus Paulo Ribeiro Machado, Alethéia Moraes Rocha, Lucas Felipe de Oliveira, Marília Beatriz de Cuba, Igor de Oliveira Loss, Lúcio Roberto Cançado Castellano, Marcos Silva, Juliana Reis Machado, Gabriel Antônio Nogueira Nascentes, Luciano Henrique Paiva, Wilson Savino, Virmondes Rodrigues, Patrı́cia C. Brum, Vânia F. Prado, Marco A. M. Prado, Eliane Lages Silva, Nicola Montano, Luı́s Eduardo Ramı́rez, Valdo José Dias da Silva   +18 more
openalex   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Preliminary evidence of cardiac dysfunction in subacute sclerosing panencephalitis: a systematic review and meta-analysis. [PDF]

Encephalitis
Pandey N, Dhiman NR, Joshi D, Raj D, Srivastava NK, Kumar A, Singh VK.   +6 more
europepmc   +1 more source