Results 251 to 260 of about 118,690 (346)

The Alzheimer's Disease Gene SORL1 Regulates Lysosome Function in Human Microglia

open access: yesGlia, EarlyView.
ABSTRACT The SORL1 gene encodes the sortilin‐related receptor protein SORLA, a sorting receptor that regulates endo‐lysosomal trafficking of various substrates. Loss of function variants in SORL1 are causative for Alzheimer's disease (AD) and decreased expression of SORLA has been repeatedly observed in human AD brains. SORL1 is highly expressed in the
Swati Mishra   +6 more
wiley   +1 more source

Thoracic autonomic nervous system surgery current application-a survey among members of the European Society of Thoracic Surgeons. [PDF]

open access: yesJ Thorac Dis
Raveglia F   +11 more
europepmc   +1 more source

Cholinergic and Glutamatergic Axons Differentially Require Glial Support in the Drosophila PNS

open access: yesGlia, EarlyView.
In the Drosophila PNS, motor‐ and sensory axons (magenta, green) differentially interact with wrapping glial processes. Sensory axons are more weakly associated with wrapping glia and show a length‐dependent degeneration upon loss of wrapping glia.
Steffen Kautzmann   +3 more
wiley   +1 more source

Perampanel monotherapy in pediatric epilepsy: Emphasizing the need for comprehensive safety evaluation

open access: yes
Epilepsia Open, EarlyView.
Gabriel Christian de Farias Morais   +8 more
wiley   +1 more source

Disruption of Oligodendroglial Autophagy Leads to Myelin Morphological Deficits, Neuronal Apoptosis, and Cognitive Decline in Aged Mice

open access: yesGlia, EarlyView.
Ablation of autophagy in oligodendrocytes reveals increased PLP expression, myelin abnormalities, axon degeneration, and increased microglia activation in aged mice. The aged mice exhibit marked deficits in learning and memory tasks. ABSTRACT The aging central nervous system (CNS) is often marked by myelin degeneration, yet the underlying mechanisms ...
Niki Ktena   +8 more
wiley   +1 more source

Unraveling the relationship between inflammation and cluster headache. [PDF]

open access: yesFront Neurol
Wang YW   +6 more
europepmc   +1 more source

Factors Increasing the Likelihood of Postoperative Hematomas Following Thyroid Surgery

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Neck hematoma following thyroid surgery is a potentially life‐threatening complication. Methods This retrospective case–control study reviewed neck hematoma reoperations following thyroid surgery (2009–2024), using 3:1 matching. Univariable analysis identified hematoma and delayed onset (≥ 6 h) risk factors, with odds ratios (ORs ...
Emily Ajit‐Roger   +9 more
wiley   +1 more source

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