A Novel Model of Cancer-Induced Peripheral Neuropathy and the Role of TRPA1 in Pain Transduction [PDF]
Background. Models of cancer-induced neuropathy are designed by injecting cancer cells near the peripheral nerves. The interference of tissue-resident immune cells does not allow a direct contact with nerve fibres which affects the tumor microenvironment and the invasion process. Methods.
arxiv +1 more source
Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment
Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality.
V. Serhiyenko, A. Serhiyenko
semanticscholar +1 more source
Cardiac Autonomic Neuropathy in Diabetes Mellitus.
Cardiovascular autonomic neuropathy (CAN) is a severely debilitating yet underdiagnosed condition in patients with diabetes. The prevalence can range from 2.5% (based on the primary prevention cohort in the Diabetes Control and Complications Trial) to as
Shruti Agashe, S. Petak
semanticscholar +1 more source
The role of autonomic neuropathy in predicting ovarian hyperstimulation syndrome
Background: Ovarian hyperstimulation syndrome (OHSS) is a life-threatening iatrogenic complication of ovarian stimulation during the assisted reproductive technique.
Zahid Mohammed A Kadhim
doaj +1 more source
Point process models for sweat gland activation observed with noise [PDF]
The aim of the paper is to construct spatial models for the activation of sweat glands for healthy subjects and subjects suffering from peripheral neuropathy by using videos of sweating recorded from the subjects. The sweat patterns are regarded as realizations of spatial point processes and two point process models for the sweat gland activation and ...
arxiv +1 more source
Cardiac Autonomic Neuropathy in Diabetes: A Predictor of Cardiometabolic Events
Autonomic nervous system (ANS) imbalance manifesting as cardiac autonomic neuropathy in the diabetic population is an important predictor of cardiovascular events.
A. Vinik+4 more
semanticscholar +1 more source
Expression profiles of TRPV1, TRPV4, TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced neuropathy rat model [PDF]
Background: The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life. Here we aim to examine the expression profiles of transient receptor potential vanilloid 1 (TRPV1) and of transient receptor potential vanilloid 4 ...
arxiv +1 more source
DIABETIC AUTONOMIC NEUROPATHY: LITTLE KNOWN CLINICAL MANIFESTATIONS
Chronic neuropathy is the most prevalent of the diabetic complications. Distal and symmetric sensitive polyneuropathy, and autonomic compromise, particularly cardiac autonomic neuropathy,are the most studied; occasionally they are asymptomatic.
Carolina Domínguez+8 more
doaj +1 more source
On a Fractional Stochastic Hodgkin-Huxley Model [PDF]
The model studied in this paper is a stochastic extension of the so-called neuron model introduced by Hodgkin and Huxley. In the sense of rough paths, the model is perturbed by a multiplicative noise driven by a fractional Brownian motion, with a vector field satisfying the viability condition of Coutin and Marie for $\mathbb R\times [0,1]^3$.
arxiv +1 more source
A machine learning-based severity prediction tool for diabetic sensorimotor polyneuropathy using Michigan neuropathy screening instrumentations [PDF]
Background: Diabetic Sensorimotor polyneuropathy (DSPN) is a major long-term complication in diabetic patients associated with painful neuropathy, foot ulceration and amputation. The Michigan neuropathy screening instrument (MNSI) is one of the most common screening techniques for DSPN, however, it does not provide any direct severity grading system ...
arxiv