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Nature Reviews Disease Primers, 2019 AbstractDiabetes mellitus is becoming increasingly common worldwide. As this occurs, there will be an increase in the prevalence of known comorbidities from this disorder of glucose metabolism. One of the most disabling adverse comorbidities is diabetic neuropathy.
Vijay Viswanathan +2 more
exaly +8 more sources
Clinical spectrum and diagnosis of diabetic neuropathies [PDF]
The Korean Journal of Internal Medicine, 2020 Neuropathy is the most prevalent microvascular complication of diabetes mellitus; it encompasses distal symmetric polyneuropathy, autonomic neuropathy, radiculoplexus neuropathy, mononeuropathy, and treatment-induced neuropathy.
Jeeyoung Oh
doaj +2 more sources
Current Treatment Options in Neurology, 2000 There are currently no treatments available (beyond optimal control of hyperglycemia) that arrest or reverse progressive diabetic polyneuropathy. Consultation with a diabetologist is indicated for patients with poorly controlled disease and polyneuropathy. Immunotherapy for diabetic lumbosacral plexopathy has been advocated but is not supported to date
A I, Vinik +3 more
europepmc +5 more sources
Differential diagnosis of polyneuropathies in diabetes mellitus
Медицинский совет, 2021 Diabetic polyneuropathy (DPN) is heterogeneous in its clinical course and clinical manifestations. Depending on the primary lesion of large or small nerve fibers, different onset, course and clinical manifestations of polyneuropathy are possible.
V. N. Khramilin
doaj +1 more source
Seminars in Neurology, 2015 Diabetes mellitus is a common condition and diabetics are prone to develop a spectrum of neuropathic complications ranging from symmetric and diffuse to asymmetric and focal neuropathies that may be associated with significant morbidity. Diabetic sensorimotor polyneuropathy is the most common of these complications, occurring in patients with type 1 ...
Aaron, Izenberg +2 more
openaire +2 more sources
Experimental and Clinical Endocrinology & Diabetes, 2014 Neuropathies related to diabetes mellitus can affect 60-70% of patients with diabetes. These can include peripheral polyneuropathies, mononeuropathies, and autonomic neuropathies. Control of glucose, lipids, and hypertension and cessation of smoking can limit onset and progression of these neuropathies. Besides control of the above listed risk factors,
Ziegler D, Keller J, Maier C, Pannek J
openaire +8 more sources
Foot and Ankle Clinics, 2006 In this review, an in-depth anatomic and molecular pathogenesis of diabetic neuropathy is provided. Classifications and clinical manifestations of diabetic neuropathy are discussed. The current modalities of treatment and clinical research on this disorder are summarized.
Christopher, Bibbo, Dipak V, Patel
openaire +4 more sources
Value of Neurofilament Light Chain as a Biomarker in Peripheral Neuropathy [PDF]
Zhongguo quanke yixue, 2022 Neurofilament light chain (NfL) has been identified as a biomarker of axonal injury in a variety of central nervous system diseases. The value of NfL as a biomarker in peripheral neuropathy has gained increasing attention.
SUN Xiaoling, HUANG Kaiwei, WAN Xinbei, WU Ying, LI Zhijun
doaj +1 more source
Diagnosing Diabetic Neuropathy: Something Old, Something New [PDF]
Diabetes & Metabolism Journal, 2018 There are potentially many ways of assessing diabetic peripheral neuropathy (DPN). However, they do not fulfill U.S. Food and Drug Administration (FDA) requirements in relation to their capacity to assess therapeutic benefit in clinical trials of DPN ...
Ioannis N. Petropoulos +5 more
doaj +1 more source
Biomedicines, 2022 A large number of peripheral neuropathies, among which are traumatic and diabetic peripheral neuropathies, result from the degeneration of the myelin sheath, a process called demyelination.
Nicolas Tricaud +4 more
doaj +1 more source