Bortezomib is standard treatment in AL amyloidosis (AL), but is contraindicated in patients with significant neuropathy. Carfilzomib, a second‐generation proteosomal inhibitor, results in a lower incidence of neuropathy than bortezomib, but data in AL is
R. Manwani+15 more
semanticscholar +1 more source
Cardiac diabetic autonomic neuropathy
The prevalence of diabetes mellitus (DM) is steadily increasing and represents a significant public health problem. At the same time, the incidence of neurological complications of diabetes mellitus, especially diabetic polyneuropathy, is increasing ...
L. T. Akhmedzhanova+3 more
doaj +1 more source
An update on the diagnosis and treatment of diabetic somatic and autonomic neuropathy
Diabetic peripheral neuropathy (DPN) is the most common chronic complication of diabetes. It poses a significant challenge for clinicians as it is often diagnosed late when patients present with advanced consequences such as foot ulceration.
S. Azmi+5 more
semanticscholar +1 more source
Study of relationship between QTC prolongation and cardiac autonomic neuropathy in Diabetes mellitus [PDF]
Objective: Cardiac Autonomic neuropathy is one of the complications in diabetic patients. This study intends to detect the prevalence of QTc prolongation in diabetic patients as well as its relationship with cardiac autonomic neuropathy.
N Natarajan1 , M S Ramaiyah2
doaj
Aim: Diabetes mellitus is a chronic condition characterized by hyperglycemia. The objective of the study was to estimate the prevalence of cardiac autonomic neuropathy in a rural area of South India, among the known diabetics after comparing them with ...
Pradeep Sukla+3 more
doaj +1 more source
Cardiac autonomic neuropathy in type 1 and type 2 diabetes patients
BackgroundCardiac autonomic neuropathy (CAN) in diabetes is among the strongest risk markers for future global and cardiovascular mortality. The aim of this study was to analyse CAN prevalence and to compare the associations between CAN, the glycaemic ...
Anca Moţăţăianu+5 more
semanticscholar +1 more source
The potential role of benfotiamine in the treatment of diabetic cardiac autonomic neuropathy
Background. Cardiac autonomic neuropathy is a serious complication of diabetes mellitus that is strongly associated with approximately five-fold increased risk of cardiovascular mortality.
V.A. Serhiyenko+3 more
doaj +1 more source
Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite ...
Victoria L Fisher, A. Tahrani
semanticscholar +1 more source
Functional Magnetic Resonance Imaging Changes and Increased Muscle Pressure in Fibromyalgia: Insights from Prominent Theories of Pain and Muscle Imaging [PDF]
Fibromyalgia is a complicated and multifaceted disorder marked by widespread chronic pain, fatigue, and muscle tenderness. Current explanations for the pathophysiology of this condition include the Central Sensitization Theory, Cytokine Inflammation Theory, Muscle Hypoxia, Muscle Tender Point Theory, and Small Fiber Neuropathy Theory.
arxiv
Boosting EfficientNets Ensemble Performance via Pseudo-Labels and Synthetic Images by pix2pixHD for Infection and Ischaemia Classification in Diabetic Foot Ulcers [PDF]
Diabetic foot ulcers are a common manifestation of lesions on the diabetic foot, a syndrome acquired as a long-term complication of diabetes mellitus. Accompanying neuropathy and vascular damage promote acquisition of pressure injuries and tissue death due to ischaemia. Affected areas are prone to infections, hindering the healing progress.
arxiv +1 more source