Results 61 to 70 of about 638,927 (261)

Deprenyl, an old drug with new anticancer potential: Mini review [PDF]

open access: yesarXiv, 2021
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv  

Cardiac autonomic neuropathy and early progressive renal decline in patients with nonmacroalbuminuric type 1 diabetes.

open access: yesAmerican Society of Nephrology. Clinical Journal, 2015
BACKGROUND AND OBJECTIVES Cardiac autonomic neuropathy predicts future adverse renal outcomes in the general population. This study sought to determine its relationship with early progressive renal decline in type 1 diabetes.
Steven Orlov   +8 more
semanticscholar   +1 more source

Autonomic neuropathy in Fabry disease: a prospective study using the Autonomic Symptom Profile and cardiovascular autonomic function tests

open access: yesBMC Neurology, 2010
Background Fabry patients have symptoms and signs compatible with autonomic dysfunction. These symptoms and signs are considered to be due to impairment of the peripheral nervous system, but findings indicative of autonomic neuropathy in other diseases ...
Wijburg Frits A   +4 more
doaj   +1 more source

The Composite Autonomic Symptom Score 31 Questionnaire: A Sensitive Test to Detect Risk for Autonomic Neuropathy

open access: yesJournal of Diabetes Research, 2023
Background and Aims. Autonomic neuropathy is a common but often neglected complication of diabetes, prediabetes, and even in individuals with an elevated risk of diabetes.
Sondre Meling   +7 more
doaj   +1 more source

Evidence from web-based dietary search patterns to the role of B12 deficiency in chronic pain [PDF]

open access: yes, 2017
Profound vitamin B12 deficiency is a known cause of disease, but the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms as well as the relationship of eating meat and B12 levels is unclear.
arxiv   +1 more source

A case of late-onset allgrove syndrome presenting with predominant autonomic dysfunction

open access: yesAnnals of Indian Academy of Neurology, 2013
Allgrove Syndrome or triple A syndrome is a rare familial multisystem disorder characterized by achalasia, alacrima and adrenal insufficiency. The objective was to describe a case of 4A syndrome where autonomic dysfunction was the presenting feature.
Debmalya Sanyal, Shakya Bhattacharjee
doaj   +1 more source

Oral manifestations, dental management, and a rare homozygous mutation of the PRDM12 gene in a boy with hereditary sensory and autonomic neuropathy type VIII: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2017
Background Hereditary sensory and autonomic neuropathy type VIII is a rare autosomal recessive inherited disorder. Chen et al. recently identified the causative gene and characterized biallelic mutations in the PR domain-containing protein 12 gene, which
Karim Elhennawy   +5 more
doaj   +1 more source

Relationship between the Korean Version Survey of the Autonomic Symptoms Score and Cardiac Autonomic Neuropathy Parameters in Patients with Diabetic Peripheral Neuropathy [PDF]

open access: yesDiabetes & Metabolism Journal, 2014
BackgroundThe Survey of Autonomic Symptom (SAS) scale was reported as an easy instrument to assess the autonomic symptoms in patients with early diabetic neuropathy. In this study, we investigated the relationship between the SAS scale and the parameters
Sun Hee Kim   +4 more
doaj   +1 more source

A Stochastic Multiscale Model that Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases [PDF]

open access: yes, 2015
The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection away from a neuron. Under normal conditions two axonal cytoskeletal polymers microtubules and neurofilaments align longitudinally in axons and are interspersed in axonal cross-sections.
arxiv   +1 more source

Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

open access: yesMediators of Inflammation, 2020
Introduction. A neuroimmune communication exists, and compelling evidence suggests that diabetic neuropathy and systemic inflammation are linked. Our aims were (1) to investigate biomarkers of the ongoing inflammation processes including cytokines ...
Anne-Marie L. Wegeberg   +8 more
doaj   +1 more source

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