Results 101 to 110 of about 1,964,883 (291)
Evaluating a Reference Model for SAV in Urban Areas
Previous work presented a reference model for shared autonomous vehicles in urban areas supported by a systematic literature review and topic modeling.
Antonio Reis Pereira +3 more
doaj +1 more source
Hvordan kan veiledningssamtaler åpne for kritisk tenkning?
Kunnskap om tilrettelegging for kritisk tenkning er vesentlig i barnehage og skoler, i lærerutdanning og i veilederutdanning. Artikkelen presenterer og døfter eksempler på hvordan veiledningssamtaler mellom nyutdannede og deres veiledere åpner for ...
Eva Bjerkholt +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Rapid and precise intervention in disaster and medical-aid scenarios demands aerial platforms that can both survey and physically interact with their environment. This study presents the design, fabrication, modeling, and experimental validation of a one-
Shouq Almazrouei +9 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Ethics and medicine: Jehovah’s Witnesses and the new blood transfusion rules
It is against the doctrine of The Watchtower and Bible Tract Society for their followers, the Jehovah’s Witnesses, to accept blood transfusions. For this reason, this topic remains a critical issue in medical practice and ethics. Few patients can survive
D. Knapp van Bogaert, G.A. Ogunbanjo
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

