Results 61 to 70 of about 38,384 (267)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Autonomic Communication Security in Sensor Networks [PDF]

, 2006
The fact that sensor networks are deployed in wide dynamically changing environment and usually left unattended, calls for nomadic, diverse and autonomic behavior. The nature of security threats in such networks as well as the nature of the network itself raise additional security challenges, so new mechanisms and architectures must be designed to ...
Tassos Dimitriou, Ioannis Krontiris
openaire   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Patterns, Trends and Policy Processes in Spanish Secondary Education: Multiple Streams in a Multilevel Context

Central European Public Administration Review, 2014
Educational policies in Spain have been characterized by conflict and continuous changes to legislation in the Central State. However, Spain is a decentralized State and the Autonomous Communities (regions) are responsible for implementing secondary ...
Eliseo López Sánchez, Esther del Campo
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

LAS DEDUCCIONES AUTONÓMICAS EN EL IRPF PARA INCENTIVAR LA ADQUISICIÓN DE ACCIONES O PARTICIPACIONES EN SOCIEDADES, LOS BUSINESS ANGELS Y EL MERCADO ALTERNATIVO BURSÁTIL [PDF]

Revista d'Estudis Autonòmics i Federals, 2011
The autonomous communities common system includes in its system of personalincome tax (IRPF) regulatory powers to govern deductions in the contributionfor carrying out “non-company investments”.
Lilo Piña Garrido
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Open Active Transparency in Spain: Regional Conglomerates and the Role of Accounting Information

Administrative Sciences
Active transparency is developed through the provision of information by public administrations. However, for this information to be reusable, it must be offered through free licenses and open formats, two characteristics present in open data. This paper
Ricardo Curto-Rodríguez, Rafael Marcos-Sánchez, Daniel Ferrández   +2 more
doaj   +1 more source

A Cross-Layer Architecture for Autonomic Communications [PDF]

, 2006
Layered architectures are not sufficiently flexible to cope with the dynamics of wireless-dominated next-generation communications. Most existing architectures and approaches depend purely on local information and provide only poor and inaccurate information gathering at the global scale.
Mohammad Abdur Razzaque, Simon A. Dobson, Paddy Nixon   +2 more
openaire   +2 more sources