Results 71 to 80 of about 65,313 (261)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Legal AI for All: Reducing Perplexity and Boosting Accuracy in Normative Texts With Fine-Tuned LLMs and RAG

IEEE Access
This study investigates the potential of open-source Large Language Models (LLMs) to enhance the accessibility and understanding of complex legal information.
Patricio Santiago Garcia-Montero, Paulina Vizcaino, Ivan Galo Reyes-Chacon, Manuel Eugenio Morocho-Cayamcela   +3 more
doaj   +1 more source

An interactive enhanced driving dataset for autonomous driving

CoRR
The evolution of autonomous driving towards full automation demands robust interactive capabilities; however, the development of Vision-Language-Action (VLA) models is constrained by the sparsity of interactive scenarios and inadequate multimodal alignment in existing data. To this end, this paper proposes the Interactive Enhanced Driving Dataset (IEDD)
Haojie Feng, Peizhi Zhang, Mengjie Tian, Xinrui Zhang 0004, Zhuoren Li, Junpeng Huang, Xiurong Wang, Junfan Zhu, Jianzhou Wang, Dongxiao Yin, Lu Xiong 0001   +10 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Developing a Risk Recognition System Based on a Large Language Model for Autonomous Driving

Engineering Proceedings
Autonomous driving systems have the potential to reduce traffic accidents dramatically; however, conventional modules often struggle to accurately detect risks in complex environments.
Donggyu Min, Dong-Kyu Kim
doaj   +1 more source

Study on Following Car Model with Different Driving Styles Based on Proximal PolicyOptimization Algorithm [PDF]

Jisuanji kexue
Autonomous driving plays a crucial role in reducing traffic congestion and improving driving comfort.It remains of significant research importance to enhance public acceptance of autonomous driving technology.Customizing different driving styles for ...
YAN Xin, HUANG Zhiqiu, SHI Fan, XU Heng
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Experimental analysis for behavior and damage of batteries caused by collisions of structure and drones in horizontal flight

Nihon Kikai Gakkai ronbunshu
This paper aims to clarify the behavior and damage conditions of batteries when multi-rotor unmanned aerial vehicles (drones) in horizontal flight collide with a structure to obtain the engineering knowledge that serves to consider the method of the ...
Kengo TAKAHASHI, Hiroki IGARASHI, Koji MATSUMOTO, Tetsuya KIMURA   +3 more
doaj   +1 more source