Results 151 to 160 of about 1,376,357 (310)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Test-retest reliability of simulated driving performance: A pilot study
, 2013 Twenty-seven volunteers completed three simulated driving tests to determine test-retest reliability of performance on a low-cost, fixed-base computerized driving simulator.
Leveritt, Michael +3 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Autonomous driving in urban areas is challenging because it requires understanding vehicle movements, traffic rules, map topologies and unknown environments in the highly complex driving environment, and thus typical urban traffic scenarios include ...
Jichiang Tsai +3 more
core +1 more source
A simulation of autonomous and cooperative behaviours using LEGO MINDSTORMS NXT [PDF]
, 2010 This report focuses on autonomous and collaborative behaviour of robots through communications, which could be useful in battlefield or emergency situations.
Arsiratham, Jayacelan Reddiar
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Road Surface Analysis for Driving Assistance
, 2014 In order to increase the level of driving automation in future cars, it is important to address critical issues, including road monitoring for irregularities and hazard detection.
Bellone M., REINA, GIULIO
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source