Results 41 to 50 of about 11,171 (260)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Design and Development of IoT-based Harvesting Robo-Vec

open access: yesMemoria Investigaciones en Ingeniería
This article presents "Harvesting Robo-Vec" an IoT-based autonomous harvesting robot designed to enhance agricultural efficiency and precision.
Sadiq Ur Rehman, Yasmin Abdul Wahab
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Design of Fruit Harvesting Robot System Based on a Reachability and Inverse Reachability Map

open access: yesAgriEngineering
This paper proposes a fruit-harvesting robot system that improves harvesting efficiency by utilizing a Reachability Map (RM) and an Inverse Reachability Map (IRM). The proposed system accurately detects fruit locations using You Only Look Once version 5 (
Jae-Woong Han   +2 more
doaj   +1 more source

Autonomous Resonance‐Tuning Mechanism for Environmental Adaptive Energy Harvesting

open access: yesAdvanced Science, 2023
An innovative autonomous resonance‐tuning (ART) energy harvester is reported that utilizes adaptive clamping systems driven by intrinsic mechanical mechanisms without outsourcing additional energy.
Dong‐Gyu Lee   +15 more
doaj   +1 more source

Plantation and Harvesting Autonomous Locomotive (PHAL)

open access: yesJournal on Today's Ideas - Tomorrow's Technologies, 2020
Agriculture has seen quite a good growth due to the latest machinery being used to maximize yield and minimize cost. People around the world are starting to understand the inherent potential and scope of automation and robotics in agriculture. However, there are many problems which continue to prevail like the non-availability of labour, poor and ...
Chaitanya Rao, null Aditya Garg
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Energy Harvesting and Management for Wireless Autonomous Sensors

open access: yesMeasurement + Control, 2008
Executive Summary: Wireless autonomous sensors that harvest ambient energy are attractive solutions, due to their convenience and economic benefits.
Alex S. Weddell   +3 more
doaj   +1 more source

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