Results 191 to 200 of about 1,264,534 (243)

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida   +4 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild   +3 more
wiley   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

On the Design of Model Predictive Setpoint Controllers for Nonholonomic Multibody Systems

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Systems subject to constraints that are not integrable to position‐level constraints pose significant challenges for setpoint control. In particular, conventional linearization techniques may fail to yield controllable approximations, since certain directions of motion are only accessible through higher‐order interactions of the control inputs.
Mario Rosenfelder   +2 more
wiley   +1 more source

Integrating Sustainability Through Socio‐Scientific Issues in Chile: Towards a Decolonial Chemistry Education

open access: yesScience Education, Volume 110, Issue 6, Page 1530-1545, November 2026.
ABSTRACT This study examines how integrating sustainability through socio‐scientific issue (SSI) in secondary chemistry teaching shapes epistemic openness and closure from a decolonial perspective, as mediated through classroom discourse. Drawing on a co‐planned lesson on copper mining in Chile – a scientifically rich yet ethically and politically ...
Denise Quiroz‐Martínez
wiley   +1 more source

Covalent Organic Frameworks in Smart Food Packaging: Advances, Challenges, and Future Prospects

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Food preservation challenges have positioned packaging as a rapidly evolving, innovation‐driven field, with smart packaging offering transformative solutions. Among advanced materials, covalent organic frameworks (COFs) have attracted growing attention due to their permanent porosity, structural tunability, high surface area, and chemical ...
Sara Esteghlal   +3 more
wiley   +1 more source

Recent Advances in Biogas Production and Upgrading Technologies for Sustainable Energy Systems

open access: yesGCB Bioenergy, Volume 18, Issue 11, November 2026.
Biogas technology is evolving from waste treatment into an intelligent renewable energy platform. Recent advances in anaerobic digestion, pretreatment, reactor design, biomethane upgrading, and AI‐driven process control improve methane recovery, stability, and gas purity.
Temechew Dessie   +2 more
wiley   +1 more source

Evaluating Environmental DNA for Pacific Salmon Spawner Enumeration Across Diverse Freshwater Systems

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.
ABSTRACT Advancing environmental DNA (eDNA) beyond species detection could provide scalable tools for estimating fish abundance, but the predictive relationships between eDNA concentration and abundance are often system‐specific and influenced by highly variable environmental conditions.
Brock T. Burgess, Josephine C. Iacarella
wiley   +1 more source

Glycyrrhizic Acid Relieves Fatigue Induced by Acute and Chronic Exercise in Mice via Inhibition of the NF‐κB/NLRP3 Signaling Pathway

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
Molecular mechanism diagram of Gly‐A in the treatment of acute and chronic exercise‐fatigue. ABSTRACT Background Glycyrrhizic acid (Gly‐A) exhibits anti‐inflammatory and antioxidant effects in various central nervous system disorders. Acute fatigue and chronic fatigue (CF) are associated with serious physical and psychological effects.
Xin‐ying Cai   +9 more
wiley   +1 more source

Spinal Mechanisms of Testosterone Involved in Itch Regulation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Testosterone serves as an endogenous anti‐pruritic hormone underlying sex‐dependent itch differences. In the spinal dorsal horn, testosterone binds androgen receptors on GABAergic interneurons to enhance GABA release, suppressing GRPR+ − pruriceptive neurons through GABAA receptors and alleviating acute/chronic itch alongside itch‐comorbid anxiety ...
Luying Chen   +5 more
wiley   +1 more source

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