Results 251 to 260 of about 81,844 (303)

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Efficient Navigable Area Computation for Underground Autonomous Vehicles via Ground Feature and Boundary Processing. [PDF]

Sensors (Basel)
Yu M, Du Y, Zhang X, Ma Z, Wang Z.
europepmc   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

C2L3-Fusion: An Integrated 3D Object Detection Method for Autonomous Vehicles. [PDF]

Sensors (Basel)
Ngo TB, Ngo L, Phi AV, Nguyen TTHT, Nguyen A, Brown J, Perera A.   +6 more
europepmc   +1 more source

An integrated SOR and SCT model approach to exploring chinese public perception of autonomous vehicles. [PDF]

Sci Rep
Wu J, Kim ST.
europepmc   +1 more source

Rule-adaptive lane-changing trajectory planning method for autonomous vehicles driven by dynamic risk information. [PDF]

Sci Rep
Zhao J, Yan X, Zhou Z, Zhang Z.
europepmc   +1 more source

Unveiling public perceptions of battery technology in autonomous vehicles via topic modeling of news articles. [PDF]

Sci Rep
Kang I, Yang J, Kim Z.
europepmc   +1 more source

Safety Decision-Making for Autonomous Vehicles Integrating Passenger Physiological States by fNIRS. [PDF]

Cyborg Bionic Syst
Zhang X, Zheng H, Li J, Xie Z, Sun H, Wang H.   +5 more
europepmc   +1 more source

Dynamic Path Planning for Unmanned Autonomous Vehicles Based on CAS-UNet and Graph Neural Networks. [PDF]

Sensors (Basel)
Ji Y, Sun R, Wang Y, Zhu Z, Liu Z.
europepmc   +1 more source