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Assessment of Autophagosome Formation by Transmission Electron Microscopy
2011Autophagy is a complex degradative process by which cytosolic material, including organelles, is randomly sequestered within double-membrane bound vesicles termed autophagosomes and targeted for degradation. Initially described as a nutrient stress adaptation response, the process of autophagy is now recognized as a central mechanism involved in many ...
Marina, Nadal, Scott E, Gold
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ATG9 promotes autophagosome formation through interaction with LC3
Biochemical and Biophysical Research CommunicationsThe autophagosome is a double-membrane organelle that executes macroautophagy. Previous studies have shown that the autophagosome formation is driven by autophagy-related genes, among which ATG9 is the only conserved transmembrane protein and has been shown to play a critical role in the autophagosome formation.
Peiqi Xu +4 more
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[The pre-autophagosomal structure (PAS), required for the formation of autophagosome membrane].
Seikagaku. The Journal of Japanese Biochemical Society, 2003Kuninori, Suzuki, Yoshinori, Ohsumi
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