Results 191 to 199 of about 286,383 (199)

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

The glucose metabolism reprogramming of yak Sertoli cells under hypoxia is regulated by autophagy. [PDF]

BMC Genomics
Ma R, Cui Y, Yu SJ, Pan YY, He JF, Wang YY, Wang JL, Wang XY, Bai XF, Zhang H, Yang SS, Zhang Q.   +11 more
europepmc   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

Ubiquitin-specific peptidase 10 attenuates bleomycin-induced pulmonary fibrosis via modulating autophagy depending on sirtuin 6-mediated AKT/mTOR. [PDF]

Cell Biol Toxicol
Mao S, Yu N, Wang W, Mao Y, Du Y, Zhao Q, Gu X, Kang J.   +7 more
europepmc   +1 more source

The inducible role of autophagy in cell death: emerging evidence and future perspectives. [PDF]

Cell Commun Signal
Huang X, Yan H, Xu Z, Yang B, Luo P, He Q.   +5 more
europepmc   +1 more source

Conserved components of the macroautophagy machinery in Caenorhabditis elegans. [PDF]

Genetics
Zhang H, Meléndez A.
europepmc   +1 more source

Baicalin attenuates LPS-induced periodontal inflammation response by inhibiting autophagy. [PDF]

BMC Oral Health
Cheng Y, Jiang M, Qin X, Mao J, Liu Y, Zhu G.   +5 more
europepmc   +1 more source

Orthoflavivirus infection and the mTOR signaling pathway. [PDF]

Front Microbiol
Zhang Y, Ba J, Luan J, Qi Z, Liu B.
europepmc   +1 more source

Autophagy in tumor immune escape and immunotherapy. [PDF]

Mol Cancer
Wang H, Sun P, Yuan X, Xu Z, Jiang X, Xiao M, Yao X, Shi Y.   +7 more
europepmc   +1 more source