Results 191 to 200 of about 687,627 (397)
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Advanced Science, EarlyView.Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu +16 morewiley +1 more sourceExploring the Therapeutic Potential of β-Hydroxybutyrate (BHB) in Clear Cell Renal Cell Carcinoma: A Journey into Fat Browning, Autophagy, and Tumor Slimming
International Journal of Clinical PracticeThis study delves into the therapeutic potential of β-hydroxybutyrate (BHB) in clear cell renal cell carcinoma (ccRCC), a cancer known for its complex pathogenesis and resistance to conventional treatments.Roya Rezaei, Asra Abdali Larki, Rosa Hosseinzadegan, Zahra Dashti, Saba Tarkashvand, Reihaneh Akhoondi, Morvarid Siri, Mesbah Shams, Alireza Monsef, Sanaz Dastghaib +9 moredoaj +1 more sourceGuidelines for the use and interpretation of assays for monitoring autophagy
, 2012 D. Klionsky, Fábio Camargo Abdalla, H. Abeliovich, Robert T. Abraham, Abraham Acevedo-Arozena, K. Adeli, Lotta Agholme, M. Agnello, P. Agostinis, J. Aguirre-Ghiso, Hyung Jun Ahn, Ouardia Ait-Mohamed, Slimane Ait-Si-Ali, T. Akematsu, Shizou Akira, H. Al-Younes, Munir A. Al‐Zeer, Matthew Albert, R. L. Albin, J. Alegre-Abarrategui, M. F. Aleo, M. Alirezaei, Alexandru Almasan, M. Almonte-Becerril, Atsuo Amano, Ravi K. Amaravadi, Shoba Amarnath, Amal O. Amer, Nathalie Andrieu-Abadie, V. Anantharaman, David K. Ann, S. Anoopkumar‐Dukie, Hiroshi Aoki, N. Apostolova, Giuseppe Arancia, John P. Aris, K. Asanuma, N. Asare, Hisashi Ashida, V. Askanas, David S. Askew, P. Auberger, M. Baba, Steven K. Backues, E. Baehrecke, Ben A. Bahr, Xue-Yuan Bai, Yannick Bailly, R. Baiocchi, G. Baldini, W. Balduini, Andrea Ballabio, B. Bamber, Edward T. W. Bampton, G. Bánhegyi, Clinton R. Bartholomew, D. Bassham, Robert C. Bast, H. Batoko, Boon-Huat Bay, Isabelle Beau, Daniel M. Béchet, Thomas J. Begley, Christian Behl, Christian Behrends, Soumeya Bekri, Bryan Bellaire, L. Bendall, Luca Benetti, L. Berliocchi, Henri Bernardi, F. Bernassola, Sébastien Besteiro, I. Kiššová, Xiaoning Bi, M. Biard-Piechaczyk, Janice S. Blum, L. Boise, P. Bonaldo, David L. Boone, B. Bornhauser, K. Bortoluci, Ioannis Bossis, F. Bost, Jean-Pierre Bourquin, Patricia Boya, Michaël Boyer-Guittaut, P. Bozhkov, N. R. Brady, Claudio Brancolini, A. Brech, J. Brenman, A. Brennand, E. Bresnick, P. Brest, Dave Bridges, Molly L Bristol, Paul S. Brookes, Eric J. Brown, J. Brumell, N. Brunetti‐Pierri, Ulf T. Brunk, Dennis E. Bulman, S. Bultman, G. Bultynck, Lena F. Burbulla, Wilfried Bursch, Jonathan P Butchar, W. Buzgariu, S. Bydlowski, Ken Cadwell, M. Cahova, Dongsheng Cai, Jiyang Cai, Qian Cai, Bruno Calabretta, Javier Calvo-Garrido, N. Camougrand, M. Campanella, J. Campos-Salinas, E. Candi, Lizhi Cao, Allan Caplan, S. Carding, Sandra M. Cardoso, J. Carew, Cathleen R Carlin, V. Carmignac, Letícia de Am Carneiro, Serena Carra, R. Caruso, G. Casari, Caty Casas, R. Castino, E. Cebollero, Francesco Cecconi, J. Celli, Hassan Chaachouay, H. Chae, C.‐Y. Chai, David C. Chan, Edmond Y W Chan, Raymond Chuen-Chung Chang, Chi-Ming Che, Ching-Chow Chen, Guang-Chao Chen, Guo-Qiang Chen, Min Chen, Quanliang Chen, Steve S.-L. Chen, Wen li Chen, Xi Chen, Xiangmei Chen, Xiequn Chen, Ye-Guang Chen, Yingyu Chen, Yongqiang Chen, Yu-Jen Chen, Zhixiang Chen, Alan Cheng, Christopher H. K. Cheng, Yan Cheng, Heesun Cheong, Jae Ho Cheong, Sara Cherry, R. Chess-Williams, Z. H. Cheung, É. Chevet, Hui-Ling Chiang, R. Chiarelli, Tomoki Chiba, L. Chin, Shih‐Hwa Chiou, F. Chisari, C. H. Cho, Dong-Hyung Cho, Augustine M. K. Choi, Doo Seok Choi, Kyeong Beom Choi, Mary E. Choi, Salem Chouaib, D. Choubey, V. Choubey, Charleen T. Chu, Tsung-Hsien Chuang, S. Chueh, Taehoon Chun, Y. Chwae, M. Chye, R. Ciarcia, M. Ciriolo, Michael J. Clague, Robert S. B. Clark, P.G.H. Clarke, Robert Clarke, Patrice Codogno, H. Coller, M. I. Colombo, S. Comincini, M. Condello, F. Condorelli, Mark R. Cookson, Graham H. Coombs, Isabelle Coppens, Ramón Corbalán, Pascale Cossart, P. Costelli, S. Costes, Ana Coto-Montes, E. Couve, F. Coxon, J. Cregg, José L. Crespo, Marianne J. Cronjé, Ana Maria Cuervo, Joseph J. Cullen, M. Czaja, M. D’Amelio, A. Darfeuille-Michaud, Lester M. Davids, Faith E. Davies, M. Felici, J. D. Groot, C. D. Haan, L. Martino, A. Milito, V. Tata, Jayanta Debnath, A. Degterev, Benjamin Dehay, L. Delbridge, F. Demarchi, Yi Deng, Jörn Dengjel, Paul Dent, Donna Denton, V. Deretic, Shyamal D. Desai, R. Devenish, M. Gioacchino, G. D. Paolo, C. D. Pietro, Guillermo Díaz-Araya, I. Díaz-Laviada, Maria T. Diaz-Meco, J. Díaz-Nido, I. Dikič, S. Dinesh-Kumar, Wen-Xing Ding, C. Distelhorst, A. Diwan, M. Djavaheri-Mergny, S. Dokudovskaya, Zheng Dong, F. C. Dorsey, V. E. Dosenko, James J. Dowling, Stephen J. Doxsey, Marlène Dreux, Mark E. Drew, Qiuhong Duan, M. Duchosal, Karen Duff, Isabelle Dugail, Madeleine Durbeej, M. Duszenko, Charles L. Edelstein, Aimee L. Edinger, Gustavo Egea, Ludwig Eichinger, N Tony Eissa, S. Ekmekcioglu, W. El-Deiry, Z. Elazar, Mohamed Elgendy, L. Ellerby, K. Eng, Anna-Mart Engelbrecht, S. Engelender, J. Erenpreisa, Ricardo Escalante, A. Esclatine, E. Eskelinen, L. Espert, V. Espina, Huizhou Fan, Jia Fan, Qianyu Fan, Zhen Fan, Shengyun Fang, Yongqi Fang, M. Fanto, A. Fanzani, T. Farkas, Jean-Claude Farré, Mathias Faure, M. Fechheimer, Carl G. Feng, Jian Feng, Qili Feng, Youjian Feng, László Fésüs, R. Feuer, M. Figueiredo-Pereira, G. Fimia, D. Fingar, Steven Finkbeiner, Toren Finkel, Kim D. Finley, M. Florez-McClure, Salvatore Florio, E. Fon, Francesco Fornai, Franco Fortunato, R. Fotedar, Daniel H. Fowler, Howard Fox, Rodrigo Franco, Lisa B. Frankel, Marc Fransen, José M. Fuentes, J. Fueyo, Jun Fujii, Kozo Fujisaki, E. Fujita, Mitsunori Fukuda, R. Furukawa, Matthias Gaestel, Philippe Gailly, Małgorzata Gajewska, Brigitte Galliot, Vincent Galy, Subramaniam Ganesh, Barry Ganetzky, I. Ganley, F. Gao, George F. Gao, Jinming Gao, Lorena García, G. Garcia-Manero, M. Garcia-Marcos, Marjan Garmyn, A. Gartel, E. Gatti, Mathias Gautel, Thomas R. Gawriluk, Matthew E Gegg, Jiefei Geng, Marc Germain, J. Gestwicki, D. Gewirtz, Saeid Ghavami, Pradipta Ghosh, A. M. Giammarioli, A. Giatromanolaki, Spencer B Gibson, R. Gilkerson, M. Ginger, Henry N. Ginsberg, J. Gołąb, M. Goligorsky, P. Golstein, C. Gomez-Manzano, E. Goncu, Céline Gongora, Claudio González, Ramon Gonzalez, Cristina González-Estévez, R. González-Polo, E. González-Rey, Nikolai V. Gorbunov, S. Gorski, S. Goruppi, Roberta A. Gottlieb, D. Gozuacik, G. Granato, G. Grant, Kim N. Green, A. Gregorc, F. Gros, Charles Grose, T. W. Grunt, Philippe Gual, Jun-Lin Guan, Kun-Liang Guan, Sylvie Guichard, A. Gukovskaya, I. Gukovsky, J. Gunst, Åsa B. Gustafsson, A. Halayko, Amber Hale, S. Halonen, Maho Hamasaki, Feng Han, Ting Han, Michael K. Hancock, M. Hansen, Hisashi Harada, Masaru Harada, S. Hardt, J. Harper, Adrian L. Harris, James S. Harris, Steven D. Harris, M. Hashimoto, Jeffrey A. Haspel, Shinichiro Hayashi, L. Hazelhurst, Congcong He, You-Wen He, Marie-Josée Hébert, Kim A. Heidenreich, M. Helfrich, G. Helgason, E. Henske, Brian Herman, Paul K. Herman, Claudio Hetz, Sabine Hilfiker, Joseph A. Hill, Lynne J. Hocking, Paul Hofman, Thomas G. Hofmann, J. Höhfeld, T. Holyoake, Ming-Huang Hong, David A. Hood, G. Hotamisligil, E. Houwerzijl, M. Høyer-Hansen, Bingren Hu, Chien-An Hu, Hongchun Hu, Y. Hua, Canhua Huang, Ju Huang, Shengbing Huang, Wei‐Pang Huang, Tobias B. Huber, Won-Ki Huh, T. Hung, Tedd R Hupp, Gangmin Hur, James B. Hurley, Sabah N. A. Hussain, P. Hussey, Jung Jin Hwang, S. Hwang, Atsuhiro Ichihara, Shirin Ilkhanizadeh, K. Inoki, T. Into, V. Iovane, Juan L. Iovanna, Nancy Y. Ip, Y. Isaka, Hiroyuki Ishida, C. Isidoro, Ken-ichi Isobe, Akiko Iwasaki, Marta Izquierdo, Y. Izumi, Panu Jaakkola, M. Jäättelä, G.R. Jackson, William T. Jackson, B. Janji, M. Jendrach, Ju Hong Jeon, E. Jeung, Hongchi Jiang, Hongchi Jiang, Jean X. Jiang, Ming Jiang, Qing Jiang, Xuejun Jiang, Alberto Jiménez, Meiyan Jin, Shengkan Jin, Cheol O. Joe, T. Johansen, Daniel E. Johnson, Gail V. W. Johnson, Nicola L. Jones, Bertrand Joseph, Suresh K. Joseph, Annie M. Joubert, Gábor Juhász, L. Juillerat-Jeanneret, C. Jung, Yong-Keun Jung, Kai Kaarniranta, Allen Kaasik, Tomohiro Kabuta, M. Kadowaki, Katarina Kågedal, Y. Kamada, Vitaliy O. Kaminskyy, H. Kampinga +499 moresemanticscholar +1 more sourceEIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer
Advanced Science, EarlyView.This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang +8 morewiley +1 more sourceCCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes
Advanced Science, EarlyView.CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract
Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking, Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma +12 morewiley +1 more source
