Results 231 to 240 of about 449,405 (356)

Autophagy in proteostasis and aging in Caenorhabditis elegans. [PDF]

open access: yesCell Stress Chaperones
Lange CM, Higuchi-Sanabria R, Kumsta C.
europepmc   +1 more source

Coronavirus Replication Complex Formation Utilizes Components of Cellular Autophagy [PDF]

open access: hybrid, 2004
Erik Prentice   +4 more
openalex   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

open access: yesAdvanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li   +9 more
wiley   +1 more source

Autophagy Gene Disruption Reveals a Non-vacuolar Cell Death Pathway in Dictyostelium [PDF]

open access: hybrid, 2004
Artémis Kosta   +5 more
openalex   +1 more source

Autophagy pathway: Cellular and molecular mechanisms

open access: yesAutophagy, 2018
Li Yu, Yang Chen, S. Tooze
semanticscholar   +1 more source

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

open access: yesAdvanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li   +24 more
wiley   +1 more source

Autophagy promotes ferroptosis by degradation of ferritin

open access: yesAutophagy, 2016
W. Hou   +7 more
semanticscholar   +1 more source

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