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Assays for Autophagy II: Mitochondrial Autophagy
2014Autophagy is a bulk degradation process of cytosolic proteins and organelles through the lysosomal/vacuolar machinery. Mitophagy is a type of autophagy that selectively degrades mitochondria. Recent studies have revealed that mitophagy plays an important role in cellular mitochondrial quality control.
Tomotake, Kanki, Koji, Okamoto
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Multifaceted roles of ATM in autophagy: From nonselective autophagy to selective autophagy
Cell Biochemistry and Function, 2019The ataxia‐telangiectasia mutated (ATM) protein kinase is best known for its critical nuclear roles in the DNA damage response (DDR), cell cycle checkpoints, and the maintenance of gene stability. In this review, we highlight the multifaceted cytoplasmic functions of ATM in autophagy.
Nan Liang +3 more
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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Nature, 2006Taichi Hara +10 more
semanticscholar +1 more source
Okayama Igakkai Zasshi (Journal of Okayama Medical Association), 2023
Kohji Takei, Hiroshi Yamada
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Kohji Takei, Hiroshi Yamada
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Loss of autophagy in the central nervous system causes neurodegeneration in mice
Nature, 2006M. Komatsu +10 more
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American Journal of Respiratory and Critical Care Medicine, 2011
María Luisa Escobar +2 more
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María Luisa Escobar +2 more
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Induction of autophagy and inhibition of tumorigenesis by beclin 1
Nature, 1999X. H. Liang +6 more
semanticscholar +1 more source
Autophagy as a target for anticancer therapy
Nature Reviews Clinical Oncology, 2011Filip Janku, Razelle Kurzrock
exaly