Results 31 to 40 of about 214,057 (309)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Autopsy in a Neonatal Intensive Care Unit: pathological and clinical agreement
Jornal de Pediatria, 2022 Objectives: To evaluate neonatal autopsy rates at a tertiary hospital in southern Brazil ascertain the level of agreement between premortem and postmortem diagnosis. Methods: The authors reviewed all neonatal autopsies performed over a 10-year period and
Camila Penso +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Egyptian Journal of Forensic SciencesBackground Myocardial bridging (MB) is a congenital coronary anomaly characterized by a segment of coronary artery passing an intramuscular course through the myocardium.
Emre Nuri İgde +4 more
doaj +1 more source
The evolution of minimally invasive tissue sampling in postmortem examination: a narrative review
Global Health Action, 2020 Background Because of low acceptance rates and limited capacity, complete diagnostic autopsies (CDAs) are seldom conducted in low- and middle-income countries (LMICs).
Christina R. Paganelli +8 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 1997 Often in tropical practice there is not time or conditions to do a proper autopsy on a patient who has died. A needle biopsy technique is described for limited closed autopsy examination to clariffy organ histology. In this way the clinician may resolve puzzling fatal disease.
openaire +4 more sources
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
GOODPASTURE SYNDROME: CASE REPORT
Проблеми екології та медицини, 2019 The Goodpasture syndrome is an immune-inflammatory pathology characterized by the formation of autoantibodies directed against the basement membranes of the renal glomeruli and pulmonary alveoli, manifested by hemorrhagic pneumonitis in combination with ...
I.I. Starchenko +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source