Results 41 to 50 of about 403,030 (353)

‘Dead people don’t claim’: A psychopolitical autopsy of UK austerity suicides [PDF]

, 2017
One of the symptoms of post financial crisis austerity in the UK has been an increase in the numbers of suicides, especially by people who have experienced welfare reform.
Armstrong J, Baumberg B, BBC, Burstow B, Butler J, Byrne P, Chakelian A, Chandler E, China Mills, Darley K, Doughty S, Fanon F, Fanon F, Froggett L, Hook D, Howell D, Loomba A, Lyons J, Marsh I, Marsh I, McDonald C, McGrath L, McVeigh K, McVeigh K, Nandy A, Napier A, O’Neill B, Pring J, Pring J, Pring J, Razack SH, Reynolds V, Rimke H, Rockett K, Ryan F, Sartre JP, Shields M, Stuckler D, Thomsen RJ, Traynor L, Tyler I, White J, WHO, Wynne-Jones R, Zizek S   +44 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The evolution of minimally invasive tissue sampling in postmortem examination: a narrative review

Global Health Action, 2020
Background Because of low acceptance rates and limited capacity, complete diagnostic autopsies (CDAs) are seldom conducted in low- and middle-income countries (LMICs).
Christina R. Paganelli, Norman J. Goco, Elizabeth M. McClure, Kathryn K. Banke, Dianna M. Blau, Robert F. Breiman, Clara Menéndez, Natalia Rakislova, Quique Bassat   +8 more
doaj   +1 more source

Rates and Causes of Death in Chiradzulu District, Malawi, 2008: A Key Informant Study [PDF]

, 2010
In September 2008, we measured all-cause mortality in Chiradzulu District, Malawi (population 291 000) over a 60-day retrospective period, using capture-recapture analysis of three lists of deaths provided by (i) key community informants, (ii) graveyard ...
Adjuik, Baiden, Doctor, Fienberg, Hosegood, International Working Group for Disease Monitoring and Forecasting, Jahn, Mathers, Roberts, Setel, World Health Organization   +10 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Exploring the relationships between cardiac conditions and myocardial bridging in sudden cardiac death: a case control autopsy study

Egyptian Journal of Forensic Sciences
Background Myocardial bridging (MB) is a congenital coronary anomaly characterized by a segment of coronary artery passing an intramuscular course through the myocardium.
Emre Nuri İgde, Burak Tastekin, Fatma Tuğba Erkman, Doğuş Özdemir Kara, Ramazan Akcan   +4 more
doaj   +1 more source

Rising plasma nociceptin level during development of HCC: A case report [PDF]

, 2004
AIM: Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC), relatively few reports are available on HCC in primary biliary cirrhosis.
Folhoffer, Anikó, Halász, Judit, Hantos, Mónika Beatrix, Horváth, Andrea, Illyés, György, Lakatos, Péter László, Schaff, Zsuzsa, Szalay, Ferenc, Tekes, Kornélia   +8 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

GOODPASTURE SYNDROME: CASE REPORT

Проблеми екології та медицини, 2019
The Goodpasture syndrome is an immune-inflammatory pathology characterized by the formation of autoantibodies directed against the basement membranes of the renal glomeruli and pulmonary alveoli, manifested by hemorrhagic pneumonitis in combination with ...
I.I. Starchenko, N.I. Vynnyk, S.M. Sovhyria, B.M. Filenko, S.А. Proskurnia, N.V. Royko, A.P. Khazanov   +6 more
doaj   +1 more source

The ethical implications of verbal autopsy: responding to emotional and moral distress

BMC Medical Ethics, 2021
Background Verbal autopsy is a pragmatic approach for generating cause-of-death data in contexts without well-functioning civil registration and vital statistics systems.
Alex Hinga, Vicki Marsh, Amek Nyaguara, Marylene Wamukoya, Sassy Molyneux   +4 more
doaj   +1 more source