Results 1 to 10 of about 98,858 (333)

Gene autoregulation by 3’ UTR-derived bacterial small RNAs

eLife, 2020
Negative feedback regulation, that is the ability of a gene to repress its own synthesis, is the most abundant regulatory motif known to biology. Frequently reported for transcriptional regulators, negative feedback control relies on binding of a ...
Mona Hoyos, Michaela Huber, Konrad U Förstner, Kai Papenfort   +3 more
doaj   +1 more source

Case report: Continuous spinal cord physiologic monitoring following traumatic spinal cord injury—A report from the Winnipeg Intraspinal Pressure Study (WISP)

Frontiers in Neurology, 2023
IntroductionAcute traumatic spinal cord injury is routinely managed by surgical decompression and instrumentation of the spine. Guidelines also suggest elevating mean arterial pressure to 85 mmHg to mitigate secondary injury.
Perry Dhaliwal, Alwyn Gomez, Alwyn Gomez, Frederick Adam Zeiler, Frederick Adam Zeiler, Frederick Adam Zeiler, Frederick Adam Zeiler, Frederick Adam Zeiler, Frederick Adam Zeiler   +8 more
doaj   +1 more source

Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression [PDF]

, 2017
Cells may control fluctuations in protein levels by means of negative autoregulation, where transcription factors bind DNA sites to repress their own production.
Lengyel, Iván M., Morelli, Luis G.
core   +2 more sources

Individualized perfusion targets in hypoxic ischemic brain injury after cardiac arrest

Critical Care, 2017
Secondary injury is a major determinant of outcome in hypoxic ischemic brain injury (HIBI) after cardiac arrest and may be mitigated by optimizing cerebral oxygen delivery (CDO2).
Mypinder S. Sekhon, Donald E. Griesdale
doaj   +1 more source

Emergence of Mechano-Sensitive Contraction Autoregulation in Cardiomyocytes

Life, 2021
The heart has two intrinsic mechanisms to enhance contractile strength that compensate for increased mechanical load to help maintain cardiac output. When vascular resistance increases the ventricular chamber initially expands causing an immediate length-
Leighton Izu, Rafael Shimkunas, Zhong Jian, Bence Hegyi, Mohammad Kazemi-Lari, Anthony Baker, John Shaw, Tamas Banyasz, Ye Chen-Izu   +8 more
doaj   +1 more source

Impact of impaired cerebral blood flow autoregulation on electroencephalogram signals in adults undergoing propofol anaesthesia: a pilot study

BJA Open, 2022
Background: Cerebral autoregulation actively maintains cerebral blood flow over a range of MAPs. During general anaesthesia, this mechanism may not compensate for reductions in MAP leading to brain hypoperfusion.
Elsa Manquat, Hugues Ravaux, Manuel Kindermans, Jona Joachim, José Serrano, Cyril Touchard, Joaquim Mateo, Alexandre Mebazaa, Etienne Gayat, Fabrice Vallée, Jérôme Cartailler   +10 more
doaj  

Insights into Neonatal Cerebral Autoregulation by Blood Pressure Monitoring and Cerebral Tissue Oxygenation: A Qualitative Systematic Review

Children, 2023
Objective: The aim of this qualitative systematic review was to identify publications on blood pressure monitoring in combination with cerebral tissue oxygenation monitoring during the first week after birth focusing on cerebral autoregulation.
Daniel Pfurtscheller, Nariae Baik-Schneditz, Bernhard Schwaberger, Berndt Urlesberger, Gerhard Pichler   +4 more
doaj   +1 more source

Cerebral Autoregulation Is Disrupted Following a Season of Contact Sports Participation

Frontiers in Neurology, 2018
Repetitive subconcussive head impacts across a season of contact sports participation are associated with a number of deficits in brain function.
Alexander D. Wright, Alexander D. Wright, Alexander D. Wright, Alexander D. Wright, Jonathan D. Smirl, Kelsey Bryk, Kelsey Bryk, Sarah Fraser, Michael Jakovac, Paul van Donkelaar   +9 more
doaj   +1 more source

Differentiating Dynamic Cerebral Autoregulation Across Vascular Territories

Frontiers in Neurology, 2021
Objective: Transcranial Doppler is commonly used to calculate cerebral autoregulation, but measurements are typically restricted to a single cerebral artery.
Navpreet Reehal, Stephanie Cummings, Michael T. Mullen, Wesley B. Baker, David Kung, William Tackett, Christopher G. Favilla   +6 more
doaj   +1 more source

Ammonia : this is not the end but rather the end of the beginning [PDF]

, 2018
Hepatic encephalopathy (HE) represents a wide spectrum of neurological or neuropsychological symptoms caused by liver disease and/or portosystemic shunts.
Dam, Gitte, Rose, Christopher, Weiss, Nicolas   +2 more
core   +1 more source