Early Autonomic Dysfunction Following Severe TBI and Impact on Cerebral Hemodynamics: A Narrative Review. [PDF]
Monten K +6 more
europepmc +1 more source
SUMMARY Alternative splicing (AS) is a common gene regulatory mechanism involving distinct interactions between trans‐acting factors and cis‐regulatory elements on the precursor messenger RNA (pre‐mRNA). In this study, we have functionally characterized the structured motif 45ABC, which is located in the pre‐mRNAs of RNA‐binding protein (RBP) 45 genes ...
Maren Reinhardt +5 more
wiley +1 more source
Liver transplant and impact on cerebral autoregulation: a systematic scoping review. [PDF]
Rochat T +4 more
europepmc +1 more source
Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya +2 more
wiley +1 more source
Autoregulation during blood flow restricted exercise offers no additional benefit on thigh muscle hypertrophy and strength adaptations in trained participants: a randomized within-subject 8-week trial. [PDF]
Akçay N +7 more
europepmc +1 more source
Autoregulation-Guided Blood Pressure Targets After Stroke Thrombectomy: Impact on Secondary Brain Injury and Neurologic Outcomes. [PDF]
Petersen NH +16 more
europepmc +1 more source
Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin +10 more
wiley +1 more source
Brain sparing in fetal growth restriction: The double‐edged sword of fetal hypoxaemia
Abstract figure legend The double‐edged sword of brain sparing. Fetal hypoxaemia triggers a coordinated adaptive response characterised by redistribution of cardiac output toward essential organs, including the brain, and a reduction in overall metabolic activity to preserve oxygen supply.
Beth J. Allison +3 more
wiley +1 more source
Multiscale modeling of blood circulation with cerebral autoregulation and network pathway analysis for hemodynamic redistribution in the vascular network with anatomical variations and stenosis conditions. [PDF]
Liu J +4 more
europepmc +1 more source
Abstract Traumatic brain injury (TBI) is associated with cardiovascular dysfunction that worsens clinical outcomes, yet the underlying mechanisms are poorly understood. Clinical studies are limited by heterogeneity, highlighting the need for controlled experimental models.
Preston So +8 more
wiley +1 more source

