Results 131 to 140 of about 36,307 (249)

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

NIRS-assisted cerebral autoregulation in elderly patients during thoracic surgery: a prospective observational study. [PDF]

BMC Anesthesiol
Shen M, Tan J, Hao Y, Hao X, Li Y, Zhuang P.   +5 more
europepmc   +1 more source

Mapping the beating heart in 4D to interrelate electrophysiology and mechanics

The Journal of Physiology, EarlyView.
Laura Bear, Callum M Zgierski‐Johnston
wiley   +1 more source

Inhibiting the Endothelial Mechanosensitive Channel Piezo1 Restores Hippocampal Blood–Brain Barrier Integrity to Improve Anesthesia‐ and Surgery‐Induced Cognitive Decline

MedComm, Volume 7, Issue 8, August 2026.
Approximately 10%–30% of elderly patients develop cognitive decline after surgery. How brain regions coordinate cellular networks to mediate this remains unclear. Anesthesia/surgery induces Piezo1 in hippocampal endothelial cells of aged mice. Endothelial Piezo1 deletion restores BBB integrity and improves cognition.
Yong Qiu, Chunheng Mo, Jinyan Wu, Jiachen Li, Shiyu Xu, Lu Chen, Liyin Zhang, Xingming Huang, Yi Zhang, Meng Sun, Yi Kang, Tao Zhu, Bi‐Sen Ding, Guo Chen   +13 more
wiley   +1 more source

Personalizing brain perfusion in traumatic brain injury. [PDF]

Crit Care Sci
Marcos-Morales A, Meyfroidt G.
europepmc   +1 more source

Fetal Brain Abnormalities Following Laser Surgery for Twin‐to‐Twin Transfusion Syndrome: Imaging Patterns and Evolution

Prenatal Diagnosis, Volume 46, Issue 9, Page 1455-1467, August 2026.
ABSTRACT Introduction Severe brain injury has been reported following fetoscopic laser ablation (FLA) for twin‐to‐twin transfusion syndrome (TTTS), but imaging patterns and temporal evolution remain poorly defined. This study aimed to characterize the progression of severe brain injury after FLA. Methods We conducted a retrospective case series of TTTS
Yada Kunpalin, Elka Miller, Ingrid Larsen, Kamini Raghuram, Catherine Windrim, Nimrah Abbasi, Greg Ryan, Tim Van Mieghem, Shiri Shinar   +8 more
wiley   +1 more source

Commentary on: "Impact of Nimodipine-Induced Blood Pressure Reductions on Cerebral Autoregulation and Functional Outcome after Aneurysmal Subarachnoid Hemorrhage". [PDF]

Neurocrit Care
Veldeman M.
europepmc   +1 more source

Impact of Higher Versus Lower Blood Pressure Targets on Pulmonary Vascular Hemodynamics During Intensive Care After Out‐of‐Hospital Cardiac Arrest

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Hemodynamic management after out‐of‐hospital cardiac arrest (OHCA) is critical, yet the impact of vasopressor‐driven mean arterial pressure (MAP) targets on pulmonary circulation and right ventricular (RV) function remains unclear.
Shira K. Hendin, Rasmus P. Beske, Jesper Kjaergaard, Jacob E. Møller, Henrik Schmidt, Simon Mølstrøm, Simon Schneekloth, Martin A. S. Meyer, Laust E. W. Obling, Christian Hassager, Johannes Grand   +10 more
wiley   +1 more source

Cerebral Autoregulation Monitoring to Evaluate for Clinical Outcome After Decompressive Hemicraniectomy for Acute Ischemic Stroke: Case Series. [PDF]

Reports (MDPI)
Alexander JE, Felbaum DR, Mai JC, Chang JJ.   +3 more
europepmc   +1 more source

First‐In‐Human Study: Dose Expansion of E7130 in Urothelial Carcinoma and Squamous Cell Carcinoma of the Head and Neck

Cancer Science, Volume 117, Issue 8, Page 2247-2258, August 2026.
The dose escalation part of the first‐in‐human study of E7130 in patients with advanced solid tumors determined the Recommended Phase 2 Dose of E7130 (480 μg/m2 Q3W). The dose expansion part (presented here) examined safety/preliminary efficacy in patients with squamous cell carcinoma of the head and neck and urothelial carcinoma.
Nobuaki Matsubara, Ken Saijo, Yasushi Shimizu, Susumu Okano, Kenji Nakano, Naoki Nishio, Tomoyuki Otsuka, Hirofumi Kuno, Takuma Miura, Tomoki Kubota, Hiroki Ikezawa, Yuko Umetsu, Ken Ito, Abraham Apfel, Yuanqing Ye, Yoshitaka Honma   +15 more
wiley   +1 more source