Results 111 to 120 of about 36,307 (249)

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro

The Journal of Physiology, EarlyView.
Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo, José M. Murrieta‐Coxca, Christian Schmeer, Lingyu Wei, Frank Steiniger, Tanja Groten, Udo R. Markert, Diana M. Morales‐Prieto   +7 more
wiley   +1 more source

Compensatory evolution facilitates loss of prfB autoregulation in Pseudomonas fluorescens SBW25. [PDF]

Mol Biol Evol
Lim S, Bertels F, Lopez-Garrido J, Gallie J.   +3 more
europepmc   +1 more source

Microcirculation and Cerebrovascular Autoregulation in Patients With Mechanical Circulatory Support Devices. [PDF]

J Stroke
Soulé Z, Wang S, Cao M, Jeong HG, Ahmad YB, Fan L, Whitman G, Cho SM.   +7 more
europepmc   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, Volume 30, Issue 4, Page 460-470, August 2026.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Lower cardiac output is a risk factor for faster cerebral atrophy over a 11‐year follow‐up period in APOE‐ε4 carriers

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Subclinical lower cardiac output (volume of blood pumped per minute) cross‐sectionally relates to smaller cerebral gray matter volumes in older adults. This study relates cardiac output to longitudinal gray matter volumes among middle‐aged and older adults over an 11‐year period.
Elizabeth E. Moore, Panpan Zhang, Omair A. Khan, Dandan Liu, Deepak K. Gupta, Kimberly R. Pechman, Katherine A. Gifford, Bennett A. Landman, Timothy J. Hohman, Angela L. Jefferson   +9 more
wiley   +1 more source

Beyond intracranial pressure: Cerebrospinal fluid compartmentalization in spaceflight‐associated neuro‐ocular syndrome

Experimental Physiology, EarlyView.
Susan P. Mollan, Damian M. Bailey
wiley   +1 more source

Visit‐to‐visit systolic blood pressure variability, blood pressure treatment intensity, and cognitive decline

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Visit‐to‐visit blood pressure variability (BPV) may be associated with cognitive decline beyond mean blood pressure (BP), but its relevance across treatment contexts remains uncertain. METHODS We pooled individual‐participant data from Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes (ACCORD‐MIND) and Systolic ...
Yue Qiao, Zihan Sun, Xunming Ji, Hugh S Markus, Wenbo Zhao   +4 more
wiley   +1 more source

Exercise training and dynamic cerebral autoregulation: Is adaptation possible?

Experimental Physiology, EarlyView.
Patrice Brassard
wiley   +1 more source