Results 31 to 40 of about 41,838 (271)
Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era
Advanced Science, EarlyView.This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley +1 more source
Minimum area of forests left to spontaneous development in protected areas
Journal of Forest Science, 2003 Search for ecological criteria for decisions on forests to be left to spontaneous development in specially protected areas is based on the knowledge of regularities of autochthonous or natural forests.
S. Vacek
doaj +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Arthritis &Rheumatology, Accepted Article.Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco +11 more
wiley +1 more source
iMetaOmics, EarlyView.The study framework for exploring microbial community assembly and community stability of biosynthesis gene cluster (BGC)‐containing species under thermal stress (20°C–65°C) during 39 days of spontaneous fermentation. Temperature gradients during spontaneous fermentation reshape microbial community assembly, driving pronounced succession in both ...
Shibo Ban +6 more
wiley +1 more source
Acidic C-terminal domains autoregulate the RNA chaperone Hfq
eLife, 2017 The RNA chaperone Hfq is an Sm protein that facilitates base pairing between bacterial small RNAs (sRNAs) and mRNAs involved in stress response and pathogenesis. Hfq possesses an intrinsically disordered C-terminal domain (CTD) that may tune the function
Andrew Santiago-Frangos +3 more
doaj +1 more source
Experimental Physiology, 2023 Surgical aortic valve replacement (SAVR) alters the natural course of severe aortic stenosis (AS). In this study, we aimed to determine the effects of the disease on dynamic cerebral autoregulation and vasoreactivity (VR) and to assess their changes ...
Tiago Pedro +7 more
doaj +1 more source
Journal of Parenteral and Enteral Nutrition, EarlyView.Abstract Background Early enteral nutrition is recommended for critically ill patients. However, feeding an ischemic gastrointestinal tract with enteral nutrition may lead to gut necrosis. Although gut tolerance of enteral nutrition is assessed by various symptoms, none of them provide conclusive evidence of gut ischemia. We investigated the blood flow
Tomonori Narita +8 more
wiley +1 more source
Autoregulation of Hepatic Circulation
Japanese Heart Journal, 1966 (1) The pressure-flow relations in both the hepatic artery and the portal vein system were investigated in a total of 13 dog livers, perfused with the homologous blood by a pump oxygenator. In addition, the interaction between the hepatic artery and the portal vein system was also studied.
J, Takeuchi +4 more
openaire +3 more sources
Relevance of dynamic cerebral autoregulation after acute ischemic stroke with prognosis: A protocol for systematic review and meta-analysis [PDF]
, 2022 Kai Wang +7 more
openalex +1 more source