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Metformin as a Disease-Modifying Agent in Autosomal Dominant Polycystic Kidney Disease: A Systematic Review of Preclinical and Clinical Evidence. [PDF]

Curr Issues Mol Biol
Maciejczyk A, Niemczyk M.
europepmc   +1 more source

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Autosomal Dominant Polycystic Kidney Disease

Primary Care: Clinics in Office Practice, 2020
Autosomal Dominant Polycystic Kidney Disease is an inherited multisystemic disorder of the renal tubules with subsequent formation of multiple cysts and enlargement of the kidney, affecting various organs. Diagnosis is initially suspected in those with family history and/or individuals who develop hypertension early on (secondary hypertension) or ...
Parvathi, Perumareddi, Darin P, Trelka
openaire   +3 more sources

Autosomal dominant polycystic kidney disease

The Lancet, 2007
Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal, monogenic disorder. It is associated with large interfamilial and intrafamilial variability, which can be explained to a large extent by its genetic heterogeneity and modifier genes.
Vicente E, Torres, Peter C, Harris, Yves, Pirson   +2 more
openaire   +2 more sources

Autosomal Dominant Polycystic Kidney Disease

New England Journal of Medicine, 1990
Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease occurring in 1 in 200 to 1 in 1,000 individuals. ADPKD is characterized by cystic lesions in the kidneys and often by structural abnormalities in the gastrointestinal tract and cardiovascular system.
openaire   +3 more sources

Autosomal dominant polycystic kidney disease

2018
Based on an estimated population prevalence of between 1 in 400 and 1 in 1000, there are over 60,000 individuals with or at risk of developing complications associated with autosomal dominant polycystic kidney disease (ADPKD) in the United Kingdom. This equates to over 300,000 people in the United States and 7 million worldwide.
Albert C. M. Ong, Richard Sandford
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Autosomal Dominant Polycystic Kidney Disease

2004
Abstract Autosomal dominant polycystic kidney disease (ADPKD) typically presents in the third or fourth decade with haematuria, loin (flank) pain or hypertension. It is characterized by the progressive development and enlargement of bilateral renal cysts and often leads to end-stage renal disease (ESRD) by late middle age.
Anand K Saggar-Malik, Stefan Somlo
openaire   +1 more source

Onconephrology: The intersections between the kidney and cancer

Ca-A Cancer Journal for Clinicians, 2021
, Kenar D Jhaveri, Mark A Perazella
exaly  

American Cancer Society's report on the status of cancer disparities in the United States, 2021

Ca-A Cancer Journal for Clinicians, 2022
Farhad Islami, Carmen E Guerra, K Robin Yabroff   +2 more
exaly  

An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma

Ca-A Cancer Journal for Clinicians, 2022
Elshad Hasanov, Marion Smits, Priscilla K Brastianos   +2 more
exaly