Results 51 to 60 of about 43,436 (236)

New onset diabetes after kidney transplantation in patients with autosomal dominant polycystic kidney disease: systematic review protocol [PDF]

, 2015
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder with numerous cysts developing in bilateral kidneys.
Ajabnoor, Barua, de Mattos, Guyatt, Harris, Hernández-Fisac, Kanaan, Kidney Disease: Improving Global Outcomes Transplant Work Group, Mao, McCarthy, Menon, Moher, Oetjen, Perrone, Pietrzak-Nowacka, Pietrzak-Nowacka, Pietrzak-Nowacka, Ruderman, Shamseer, Torra, Torres, Torres, Turkmen   +22 more
core   +1 more source

Magnetic resonance imaging 3t and total fibrotic volume in autosomal dominant polycystic kidney disease [PDF]

, 2018
INTRODUCTION: Autosomal dominant polycystic kidney disease (ADPKD) is the most common renal hereditary disorder. Several authors have attempted to identify a kidney damage marker for predicting the prognosis and the effectiveness of therapy in ADPKD ...
Ciccariello, Mauro, D'Angelo, Anna Rita, DI GAETA, Alessandro, Ferrigno, Luigina, Lai, Silvia, Letizia, Claudio, Mastroluca, Daniela, Panebianco, Valeria, Perrotta, ADOLFO MARCO, Petramala, Luigi   +9 more
core   +1 more source

Aberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains Unaffected [PDF]

, 2004
Polycystin-1, the polycystic kidney disease 1 gene product, has been implicated in several signaling complexes that are known to regulate essential cellular functions. We investigated the role of polycystin-1 in Wnt signaling and activator protein-1 (
Arnould, Bhunia, Duyndam, Giles, Grotewold, Huan, Kim, Kimberling, Kugoh, Loghman-Adham, Löhning, Morin, Moser, Muto, Newby, Ouwens, Parnell, Peters, Pritchard, Rivat, Rodova, Saadi-Kheddouci, Scheffers, Shaulian, Smits, Sorenson, Spaargaren, Streets, Sutters, Trudel, Upadhya, van Adelsberg, van Dam, van Dam, van Dam, van Dam, van de Wetering, van de Wetering   +37 more
core   +8 more sources

The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease

Cell Death and Disease, 2021
Autosomal-dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease and is characterized by progressive growth of fluid-filled cysts. Growth factors binding to receptor tyrosine kinases (RTKs) stimulate cell proliferation and
Abeda Jamadar, S. Suma, Sijo Mathew, T. Fields, D. Wallace, J. Calvet, R. Rao   +6 more
semanticscholar   +1 more source

Insights into Autosomal Dominant Polycystic Kidney Disease from Genetic Studies.

American Society of Nephrology. Clinical Journal, 2020
Autosomal dominant polycystic kidney disease is the most common monogenic cause of ESKD. Genetic studies from patients and animal models have informed disease pathobiology and strongly support a "threshold model" in which cyst formation is triggered by ...
M. Lanktree, A. Haghighi, Ighli di Bari, Xuewen Song, Y. Pei   +4 more
semanticscholar   +1 more source

An Empirical Biomarker-based Calculator for Autosomal Recessive Polycystic Kidney Disease - The Nieto-Narayan Formula

, 2016
Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts.
Goldberg, Itzhak D., Narayan, Prakash, Nieto, Jake A., Yamin, Michael A.   +3 more
core   +2 more sources

Autosomal dominant polycystic kidney disease and coronary artery dissection or aneurysm: A systematic review [PDF]

, 2016
Importance Autosomal dominant polycystic kidney disease (ADPKD) has been associated with cardiovascular abnormalities such as intracranial and aortic aneurysms.
Lopes, JA, Neves, JB, Rodrigues, FB
core   +1 more source

Metabolic Reprogramming in Autosomal Dominant Polycystic Kidney Disease: Evidence and Therapeutic Potential.

American Society of Nephrology. Clinical Journal, 2020
Autosomal dominant polycystic kidney disease is characterized by progressive development and enlargement of kidney cysts, leading to ESKD. Because the kidneys are under high metabolic demand, it is not surprising that mounting evidence suggests that a ...
Kristen L. Nowak, Katharina Hopp
semanticscholar   +1 more source

Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease

iScience, 2021
Summary Progression of autosomal dominant polycystic kidney disease (ADPKD) is modified by metabolic defects and obesity. Indeed, reduced food intake slows cyst growth in preclinical rodent studies.
Katharina Hopp, Victoria Catenacci, Nidhi Dwivedi, T. Kline, W. Wang, Zhiying You, Dustin T. Nguyen, Kristen Bing, Bhavya Poudyal, Ginger C. Johnson, M. Jackman, Marsha Miller, C. Steele, N. Serkova, P. MacLean, R. Nemenoff, Berenice Y. Gitomer, M. Chonchol, Kristen L. Nowak   +18 more
semanticscholar   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source