Results 11 to 20 of about 12,592,373 (135)

Genetic Linkage Analysis of DFNB2 Locus with Autosomal Recessive Hearing Loss in Families Negative for GJB2 Mutations in Khuzestan Province [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016
Background: Hearing loss is a common sensory impairment in humans which half of its causes are genetic reasons. Genetic hearing loss can be divided into the two types of syndromic and non-syndromic, which 80% of non-syndromic cases is Autosomal Recessive
Parisa Tahmasebi, Seyed Reza Kazemi Nezhad, Mohammad Amin Tabatabaiefar, Javad Mohammadi Asl, Nader Saki   +4 more
doaj   +1 more source

Case Report: First Report of Mutation in Col 11A2 Gene in an Iranian Family with Autosomal Rrecessive Non-Syndromic Hearing Loss

Journal of Rehabilitation, 2003
Hereditary Hearing loss (HHL) affects one in 2000 netborns and more than 50% of these cases, the loss has a genetic basis. About 70% of HHL is non-syndromic with autosomal recessive mode of inheritance accounting for ~85% of the genetic load and more ...
Kimia Kahrizi, Ahmad Daneshi, Yasser Riaz-el Hosseini, Carla Nishimora, Richard Smith, Hossein Najm-Abadi   +5 more
doaj   +1 more source

Screening of Autosomal Recessive Non-Syndromic Hearing Loss gor GJB2 Mutations

Journal of Rehabilitation, 2004
Objective: Hereditary Hearing loss (HHL) affects one in 1000-2000 newborns and more than 50% of these cases, the loss has a genetic basis. About 70% of HHL is non-syndromic with autosomal recessive forms accounting for ~85% of the genetic load.
Atefeh Khosh-Aeen, Fatemeh Pourfatemi, Kimia Kahrizi, Yaser Riaz-Alhosseini, Marziyeh Mohseni, Niloufar Bazzaz-Zadegan, Nooshin Nik-Zaat, Hossein Najm-Abadi   +7 more
doaj   +1 more source

Review: Hearing Loss Genetics

Journal of Rehabilitation, 2005
It has been estimated that approximately one in 1000 live births suffer from profound deafness, and greater than 50% of this group is genetic etiology.
Hossein Najm-Abadi, Kimia Kahrizi
doaj   +1 more source

Haplotype Analysis of Seven Non-Syndromeic Autosomal Recessive Hearing Loss Loci in Iranian Families

Journal of Rehabilitation, 2010
Objective: Hearing impairment is the most frequent sensorineural defect in 2 forms, syndromic and non–syndromic. The aim of this study is haplotype analysis of seven loci of non–syndromic autosomal recessive hearing loss in Iranian families. Materials &
Ramak Badr, Bahareh Shoja-Saffar, Niloofar Bazzaz-Zadegan, Khadijeh Jalalvand, Kimia Kahrizi, Hossein Najm-Abadi   +5 more
doaj   +1 more source

Relative Frequency of 35delG Mutation in GJB2 Gene in Autosomal Recessive Non-Syndromic Hearing Loss (ARNSHL) Patients in Kerman Population [PDF]

Journal of Kerman University of Medical Sciences, 2004
Congenital hearing loss with many genetic and environmental causes affects 1 in 1000 newborns. Mutations in the GJB2(Gap Junction Beta-2) gene encoding the gap junction protein connexin 26 have been established as the main cause of autosomal recessive ...
N Bazazzadegan, N Mirhoseini, H Ziaaddini, AR Asadi, K Kahrizi, S Arzhangi, A Astani, M Mohseni, Y Riazalhosseini, M Nejat, Kh Jalalvand, RJH Smith, C Nishimura, H Najmabadi   +13 more
doaj   +2 more sources

Autosomal Recessive Non-Syndromic Deafness: Is AAV Gene Therapy a Real Chance? [PDF]

Audiology Research
The etiology of sensorineural hearing loss is heavily influenced by genetic mutations, with approximately 80% of cases attributed to genetic causes and only 20% to environmental factors.
Davide Brotto, Marco Greggio, Cosimo De Filippis, Patrizia Trevisi   +3 more
doaj   +2 more sources

Autosomal Recessive and Sporadic Non Syndromic Hearing Loss and the Incidence of Cx26 Mutations in a Province of Iran [PDF]

Iranian Journal of Public Health, 2006
Despite the enormous heterogeneity of genetic hearing loss, mutations in the GJB2 (connexin 26) gene located on “DFNB1” locus (13q12) account for up to 50% of cases of autosomal recessive non-syndromic hearing loss (ARNSHL) in some populations.
M Hashemzadeh Chaleshtori, M Montazer Zohour, L Hoghooghi Rad, H Pour-Jafari, DD Farhud, M Dolati, K Safa Chaleshtori, R Sasanfar, A Hosseinipour, L Andonian, A Tolouei, M Ghadami, MA Patton   +12 more
doaj   +5 more sources

Informativeness of D7S2456 marker for molecular diagnosis of autosomal recessive non syndromic hearing loss in five Iranian ethnic groups

مجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: SLC26A4 gene mutations after GJB2 mutations are the second currently identifiable genetic cause of autosomal recessive non syndromic hearing loss (ARNSHL) which currently is used in molecular diagnosis of ARNSHL.
Mojtabavi Naeini M, Vallian Broujeni S, Hashemzadeh Chaleshtori M   +2 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source