Results 71 to 80 of about 1,238,433 (289)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Bispinor Auxiliary Fields in Duality-Invariant Electrodynamics Revisited

, 2013
Motivated by a recent progress in studying the duality-symmetric models of nonlinear electrodynamics, we revert to the auxiliary tensorial (bispinor) field formulation of the O(2) duality proposed by us in arXiv:hep-th/0110074, arXiv:hep-th/0303192.
Ivanov, E. A., Zupnik, B. M.
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Les particularités morphosyntaxiques du créole réunionnais

Études Créoles, 2016
In this paper, I put forward an analysis of Reunion Creole on the following topics: verb inflection, auxiliaries, preverbal particles, with especial consideration of preverbal /i/. I aim at answering some crucial questions:- Is it legitimate to postulate
Jean-Philippe Watbled
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Synthesis of highly branched water-soluble polyester and its surface sizing agent strengthening mechanism

e-Polymers, 2020
Solvent-free and highly branched water-soluble polyester (WPET) is prepared through self-emulsification methodology, using dimethyl terephthalate (DMT), sodium dimethyl isophthalate-5-sulfonate (SIPM), trimethylolpropane (TMP), and ethylene glycol (EG ...
Duan Wangwang, Li Xiaorui, Shen Yiding, Yang Kai, Zhang Hua   +4 more
doaj   +1 more source

Ion-liquid based super-capacitors with inner gate diode-like separators

, 2019
We demonstrate that the capacitance of ionic-liquid filled supercapacitors is substantially increased by placing a diode-like structure on the separator membrane. We call the structured separator: gate, and demonstrate that the order of a p-n layout with
Chowdhury, Tazima S., Grebel, Haim
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Electronic levels and electrical response of periodic molecular structures from plane-wave orbital-dependent calculations

, 2011
Plane-wave electronic-structure predictions based upon orbital-dependent density-functional theory (OD-DFT) approximations, such as hybrid density-functional methods and self-interaction density-functional corrections, are severely affected by ...
Dabo, Ismaila, Li, Yanli
core   +3 more sources