Results 31 to 40 of about 296,851 (282)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Resident non-invasive load identification algorithm based on prior statistical model

电力工程技术
In this paper, a non-intrusive load identification algorithm for residents based on prior knowledge and statistical learning model is proposed to solve the problem of insufficient electric heating subdivision capability in traditional identification ...
ZHAO Cheng, SONG Yanxin, ZHOU Gan, FENG Yanjun, GUO Shuai, LI Jiwei   +5 more
doaj   +1 more source

The effect of exercise using auxiliary tools in learning the forehand and backhand skills of female tennis students

Pedagogy of Physical Culture and Sports, 2023
Background and Study Aim. The present study investigates the effect of exercise using auxiliary tools. It should facilitate learning process of the forehand and backhand skills of female tennis students of physical education and sports.
Adnan Abdullah, Wadii Zayed, Bali Naila
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Radio frequency baseband recording technique [PDF]

, 1970
Technique uses a helical-scan video recorder with auxiliary signal-conditioning equipment to provide an inexpensive, high-capacity magnetic tape recording of a 112 channel, phase-locked, multiplexed, baseband ...
Heckman, D. C.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Design and realization of a sputter deposition system for the \textit{in situ-} and \textit{in operando-}use in polarized neutron reflectometry experiments

, 2017
We report on the realization of a sputter deposition system for the in situ- and in operando-use in polarized neutron reflectometry experiments. Starting with the scientific requirements, which define the general design considerations, the external ...
Böni, Peter, Förg, Benjamin, Herrnberger, Alexander, Kreuzpaintner, Wolfgang, Mairoser, Thomas, Mannhart, Jochen, Meir, Stefan, Schmehl, Andreas, Stephanos, Cyril, Wiedemann, Birgit   +9 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Autocompensator of noise-like obstacle with correction circles based on frequency-dependent filters

Технічна інженерія, 2023
An important feature of the armed conflict in the east of Ukraine is the wide use of the means of electronic warfare by the enemy. Quite effective means that create significant obstacles to the operation of a radar station are noise-like obstacles, in ...
O.F. , Yu.M. , A.Yu. , A.S.
doaj   +1 more source