Results 41 to 50 of about 36,410 (241)

Research on Temperature Situation Awareness and Auxiliary Decision-Making System Scheme of Substation Equipment

open access: yes发电技术
ObjectivesTo enhance the intelligent management of substation equipment maintenance, timely identify and mitigate the risks of failures caused by device overheating, and ensure the safe and stable operation of the power grid, the temperature situation ...
CHEN Yu   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Methods detection place depressurization of thermal power equipment, operating under vacuum

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2017
This article considers the urgency of the problem of ensuring impermeability of vacuum system of the turbine and vacuum deaerators. Developed and successfully tested in an industrial operation highly effective instrument and without instruments methods ...
V. I. Sharapov   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

An Applied Research of Decision Tree Algorithm in Track and Field Equipment Training

open access: yesMATEC Web of Conferences, 2015
This paper has conducted a study on the applications of track and field equipment training based on ID3 algorithm of decision tree model. For the selection of the elements used by decision tree, this paper can be divided into track training equipment ...
Liu Shaoqing, Wang Kebin
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Optimization of the economic operation of independent energy storage power stations considering the dynamic power consumption constraints of main equipment and auxiliary equipment

open access: yesEnergy Conversion and Management: X
To address the systemic inadequacies and limited practicality of energy consumption modelling in existing research on the optimization of energy storage station operation, this paper proposes an economic operation optimization strategy for independent ...
Min Wang   +5 more
doaj   +1 more source

MAXIMIZING ENERGY SAVINGS ATTAINABLE BY DYNAMIC INTENSIFICATION OF BINARY DISTILLATION

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2019
Dynamic intensification of distillation columns has shown significant promise in achieving energy savings with minimal investment in new equipment. Conceptually, it entails making a desired product as a blend of two auxiliary products (one with higher ...
Lingqing YAN   +2 more
doaj   +1 more source

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