Results 161 to 170 of about 273,093 (318)

Network analysis of an OSCE-based graduation skills assessment for clinical medical students. [PDF]

BMC Med Educ
Zhang H, Li S, Zheng G, Chen X, Zhong L, Li J, Li Y.   +6 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Unique plastisphere viromes with habitat-dependent potential for modulating global methane cycle. [PDF]

Nat Commun
Chen XP, Zhu D, Liu SY, Sun MM, Ye M, Wang L, Lin D, Zhang TL, Rillig MC, Zhu YG.   +9 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Orthotopic liver transplantation [PDF]

, 1980
Starzl, TE
core  

Mitochondrial DNA Variation of the Striped Hyena (Hyaena hyaena) in Algeria and Further Insights into the Species' Evolutionary History. [PDF]

Genes (Basel)
Derouiche L, Rodrigues M, Benameur-Hasnaoui H, Aissa RH, Hassan-Beigi Y, Madjdzadeh SM, Amr Z, Cokayne A, Vercammen P, Fernandes CR.   +9 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Identification and validation of postpartum depression subtypes: a population-based cohort study. [PDF]

EClinicalMedicine
Bauer AE, Jaholkowski P, Lu Y, Guintivano J, Hannigan LJ, Corfield EC, Tesli M, Andreassen OA, Li Y, Reichborn-Kjennerud T, Sullivan PF, Meltzer-Brody S, Havdahl A, Ask H.   +13 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Factoring an integer with three oscillators and a qubit. [PDF]

Nat Commun
Brenner L, Caha L, Coiteux-Roy X, Koenig R.   +3 more
europepmc   +1 more source